Evidence map›Paper›PMID 31409480›Full record

ReviewBiophysical journal2019

Biophysics and the Genomic Sciences.

David C Schwartz

Abstract readReview
In one paragraph

Review in Biophysical journal, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

David C SchwartzDepartment of Chemistry, Laboratory of Genetics, Laboratory for Molecular and Computational Genomics, University of Wisconsin-Madison, Madison Wisconsin. Electronic address: dcschwartz@wisc.edu.

Funding

NEW PHYSICAL METHODOLOGIES FOR GENOMIC ANALYSISR01HG000225 · NHGRI · UNIVERSITY OF WISCONSIN-MADISON · PI SCHWARTZ, DAVID C. · 1991 to 2014
$5.2M
Scalable Cancer Genomics via Nanocoding and SequencingR33CA182360 · NCI · UNIVERSITY OF WISCONSIN-MADISON · PI MA, JIAN, SCHWARTZ, DAVID C. · 2015 to 2017
$1.1M
NCI NIH HHS R33 CA182360NHGRI NIH HHS R01 HG000225
6 · The paper itself

Abstract

It is now rare to find biological, or genetic investigations that do not rely on the tools, data, and thinking drawn from the genomic sciences. Much of this revolution is powered by contemporary sequencing approaches that readily deliver large, genome-wide data sets that not only provide genetic insights but also uniquely report molecular outcomes from experiments that biophysicists are increasingly using for potentiating structural and mechanistic investigations. In this perspective, I describe a path of how biophysical thinking greatly contributed to this revolution in ways that parallel advancements in computer science through discussion of several key inventions, described as "foundational devices." These discussions also point at the future of how biophysics and the genomic sciences may become more finely integrated for empowering new measurement paradigms for biological investigations.

Indexed as

BiophysicsGenomicsLab-On-A-Chip Devices

Identifiers

PMID31409480
PMCPMC6895736

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.