Evidence map›Paper›PMID 31409383›Full record

ArticleTrials2019

Influence of upper-body continuous, resistance or high-intensity interval training (CRIT) on postprandial responses in persons with spinal cord injury: study protocol for a randomised controlled trial.

David W McMillan, Jennifer L Maher, Kevin A Jacobs, Armando J Mendez, Mark S Nash, James L J Bilzon

Registry-linked trialOpen access · goldAbstract readClinical Trial Protocol
In one paragraph

Article in Trials, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03545867 (Effect of Various Forms of Upper Body Exercise on the Energetic Response to a Meal in Persons With Spinal Cord Injury), which is not on this map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03545867 nacompletednot on this map

Effect of Various Forms of Upper Body Exercise on the Energetic Response to a Meal in Persons With Spinal Cord Injury

TypeinterventionalSponsorUniversity of MiamiRan2018 to 2018Enrolled10ConditionsSpinal Cord InjuriesArmsSeated control (CON), Moderate intensity continuous (MICT), High intensity interval training (HIIT), Circuit resistance training (CRT), Liquid Meal
3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 10 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Exercise Interventions Targeting Obesity in Persons With Spinal Cord Injury.Topics in spinal cord injury rehabilitation · 2021
    Review
  5. Article
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 2 countries.

David W McMillanThe Miami Project to Cure Paralysis, University of Miami Miller School of Medicine, Miami, FL, USA.
Jennifer L MaherThe Miami Project to Cure Paralysis, University of Miami Miller School of Medicine, Miami, FL, USA.
Kevin A JacobsDepartment of Kinesiology and Sport Sciences, University of Miami, Miami, FL, USA.
Armando J MendezDivision of Endocrinology, Diabetes and Metabolism, University of Miami Miller School of Medicine, Miami, FL, USA.
Mark S NashThe Miami Project to Cure Paralysis, University of Miami Miller School of Medicine, Miami, FL, USA.
James L J BilzonThe Miami Project to Cure Paralysis, University of Miami Miller School of Medicine, Miami, FL, USA. j.bilzon@bath.ac.uk.ORCID http://orcid.org/0000-0002-6701-7603
University of Miami · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundChronic spinal cord injury (SCI) increases morbidity and mortality associated with cardiometabolic diseases, secondary to increases in central adiposity, hyperlipidaemia and impaired glucose tolerance. While upper-body Moderate Intensity Continuous Training (MICT) improves cardiorespiratory fitness, its effects on cardiometabolic component risks in adults with SCI appear relatively modest. The aim of this study is to assess the acute effects of Continuous Resistance Training (CRT), High Intensity Interval Training (HIIT), MICT and rest (CON) on fasting and postprandial systemic biomarkers and substrate utilisation.

methodsEleven healthy, chronic SCI (> 1 year, ASIA A-C) men will be recruited. Following preliminary testing, each will complete four experimental conditions, where they will report to the laboratory following an ~ 10-h overnight fast. A venous blood sample will be drawn and expired gases collected to estimate resting metabolic rate (RMR). In order to ensure an isocaloric exercise challenge, each will complete CRT first, with the remaining three conditions presented in randomised order: (1) CRT, ~ 45 min of resistance manoeuvres (weight lifting) interspersed with low-resistance, high-speed arm-crank exercise; (2) CON, seated rest; (3) MICT, ~ 45 min constant arm-crank exercise at a resistance equivalent to 30-40% peak power output (PPO) and; (4) HIIT, ~ 35 min arm-crank exercise with the resistance alternating every 2 min between 10% PPO and 70% PPO. After each ~ 45-min condition, participants will ingest a 2510-kJ liquid test meal (35% fat, 50% carbohydrate, 15% protein). Venous blood and expired gas samples will be collected at the end of exercise and at regular intervals for 120 min post meal. DISCUSSION: This study should establish the acute effects of different forms of exercise on fasting and postprandial responses in chronic SCI male patients. Measures of glucose clearance, insulin sensitivity, lipid and inflammatory biomarker concentrations will be assessed and changes in whole-body substrate oxidation estimated from expired gases.

trial registrationClinicalTrials.gov, ID: NCT03545867 . Retrospectively registered on 1 June 2018.

Indexed as

Energy MetabolismHigh-Intensity Interval TrainingPostprandial PeriodResistance TrainingBiomarkersBlood GlucoseCross-Over StudiesFastingFloridaHumansInflammation MediatorsInsulinInsulin ResistanceLipidsMaleRandomized Controlled Trials as TopicBiomarkersBlood GlucoseInflammation MediatorsInsulinLipidsContinuous resistance trainingExerciseHigh-intensity interval trainingMetabolismPostprandialSpinal cord injuryUpper-body exercise

Identifiers

PMID31409383
PMCPMC6693181
OpenAlexW2966524502

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.