Evidence map›Paper›PMID 31409036›Full record

ArticleInternational journal of molecular sciences2019

Impact of Astrocyte Depletion upon Inflammation and Demyelination in a Murine Animal Model of Multiple Sclerosis.

Lisa Allnoch, Wolfgang Baumgärtner, Florian Hansmann

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
2.9field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 37 citations in OpenAlex.

  1. Article
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  5. Ovalbumin-specific CD4Frontiers in immunology · 2023
    Article
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  7. Review
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  18. Article
  19. Human CommensalFrontiers in immunology · 2020
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Lisa AllnochDepartment of Pathology, University of Veterinary Medicine Hannover, 30559 Hannover, Germany.
Wolfgang BaumgärtnerDepartment of Pathology, University of Veterinary Medicine Hannover, 30559 Hannover, Germany. Wolfgang.Baumgaertner@tiho-hannover.de.
Florian HansmannDepartment of Pathology, University of Veterinary Medicine Hannover, 30559 Hannover, Germany.
University of Veterinary Medicine Hannover, Foundation · DE

Funding

Niedersächsische Ministerium für Wissenschaft und Kultur Niedersachsen-Research Network on Neuroinfectiology (N-RENNT)
6 · The paper itself

Abstract

Astrocytes play a key role in demyelinating diseases, like multiple sclerosis (MS), although many of their functions remain unknown. The aim of this study was to investigate the impact of astrocyte depletion upon de- and remyelination, inflammation, axonal damage, and virus distribution in Theiler`s murine encephalomyelitis (TME). Groups of two to six

Indexed as

AnimalsAstrocytesCardiovirus InfectionsDemyelinating DiseasesDisease Models, AnimalFemaleInflammationMiceMultiple SclerosisTheilovirusaquaporin 4astrocytesblood-spinal cord barrierGFAP-thymidine kinase transgenic SJL miceglial fibrillary acidic proteinTheiler`s murine encephalomyelitis

Identifiers

PMID31409036
PMCPMC6719128
OpenAlexW2968290920

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.