ArticleInternational journal of environmental research and public health2019
Long-Term Trends of Liver Cancer Incidence and Mortality in China 1990-2017: A Joinpoint and Age-Period-Cohort Analysis.
Article in International journal of environmental research and public health, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.
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Who cites it
34 citing papers in PubMed.
- Socio-demographic disparities in liver cancer mortality in China: a national analysis from 2015 to 2021.Frontiers in oncology · 2026Article
- [Predictive role of dynamic changes in liver stiffness measurement for liver-related endpoint events in chronic hepatitis B].Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2025Article
- The global burden of chronic respiratory diseases attributable to tobacco from 1990 to 2021: a global burden of disease study 2021.BMC public health · 2025Article
- Cancer situation in China: an analysis based on the global epidemiological data released in 2024.Cancer communications (London, England) · 2025Article
- Noninvasive diagnosis model for predicting significant liver inflammation in patients with chronic hepatitis B in the immune-tolerant phase.Scientific reports · 2025Article
- Long-term trends in the incidence of male breast cancer and nomogram for predicting survival in male breast cancer patients: a population-based epidemiologic study.Scientific reports · 2025Article
- Comprehensive Analysis of the Role of Heat Shock Proteins in the Immune Microenvironment and Clinical Significance of Hepatocellular Carcinoma.Journal of hepatocellular carcinoma · 2025Article
- Time trends in coronary heart disease mortality attributed to outdoor PM2.5 in China: an age-period-cohort analysis using the Global Burden of Disease Study 2019.Frontiers in public health · 2025Article
- Chinese medicine in the treatment of chronic hepatitis B: The mechanisms of signal pathway regulation.Heliyon · 2024Review
- Global, regional, and national burdens of leukemia from 1990 to 2019: A systematic analysis of the global burden of disease in 2019 based on the APC model.Cancer medicine · 2024Article
- "Treat-all" Strategy for Patients with Chronic Hepatitis B Virus Infection in China: Are We There Yet?Journal of clinical and translational hepatology · 2024Review
- Development and validation of the treatment expectation scale for patients with liver cancer.Archives of medical science : AMS · 2024Article
- Trend analysis and age-period-cohort effects on morbidity and mortality of liver cancer from 2010 to 2020 in Guangzhou, China.Frontiers in oncology · 2024Article
- The mortality of oral cancer attributable to tobacco in China, the US, and India.Journal of cancer research and clinical oncology · 2023Article
- Guidelines for the Prevention and Treatment of Chronic Hepatitis B (version 2022).Journal of clinical and translational hepatology · 2023Article
- Age-Period-Cohort Study of Breast Cancer Mortality in Brazil in State Capitals and in Non-Capital Municipalities from 1980 to 2019.International journal of environmental research and public health · 2023Article
- Cancer morbidity and mortality trends in Trinidad and Tobago (2008-2018).Journal of health, population, and nutrition · 2023Article
- [Interpretation of the essential updates in guidelines for the prevention and treatment of chronic hepatitis B (Version 2022)].Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2023Article
- Secular Trends of Liver Cancer Mortality and Years of Life Lost in Wuhan, China 2010-2019.Current oncology (Toronto, Ont.) · 2023Article
- Long-term trends in the burden of edentulism in China over three decades: A Joinpoint regression and age-period-cohort analysis based on the global burden of disease study 2019.Frontiers in public health · 2023Article
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7 authors.
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Abstract
Liver cancer (LC) is one of the most common causes of cancer-related deaths: this study aims to present the long-term trends and age-period-cohort effects of the incidence of and mortality from LC in China during 1990-2017. Incidence and mortality data were obtained from the Global Burden of Disease Study 2017. We determined trends in the age-standardized incidence rate (ASIR) and mortality rate (ASMR) using Joinpoint regression. An age-period-cohort (APC) analysis was performed to describe the long-term trends with intrinsic estimator methods. The ASMR decreased markedly before 2013 and increased thereafter, with overall average annual percent change (AAPC) values of -0.5% (95% confidence interval (CI): -0.6%, -0.3%) for men and -1.3% (-1.6%, -1.0%) for women during 1990-2017. The ASIR significantly increased by 0.2% (0.1%, 0.3%) in men and decreased by 1.1% (-1.2%, -1.0%) in women from 1990 to 2017. The risks of LC incidence and mortality increased with age in both genders. The period effect risk ratios (RRs) of incidence and mortality displayed similar monotonic increasing trends in men and remained stable in women. The cohort effect showed an overall downward trend and almost overlapping incidence and mortality in both genders, and later birth cohorts experienced lower RRs than previous birth cohorts. Older age, recent period, and birth before 1923 were associated with a higher risk of liver cancer incidence and mortality. The net age and period effects showed an increasing trend, while the cohort effects presented a decreasing trend in incidence and mortality risk. As China's population aging worsens and with the popularization of unhealthy lifestyles, the burden caused by liver cancer will remain a huge challenge in China's future.
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