Evidence map›Paper›PMID 31408932›Full record

ArticleAnimals : an open access journal from MDPI2019

Glucocorticoids and Catecholamines Affect in Vitro Functionality of Porcine Blood Immune Cells.

Lena Reiske, Sonja Schmucker, Julia Steuber, Volker Stefanski

Open access · goldAbstract read
In one paragraph

Article in Animals : an open access journal from MDPI, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.9field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Welfare of pigs on farm.EFSA journal. European Food Safety Authority · 2022
    Article
  5. Review
  6. Impact of Housing Environment on the Immune System in Chickens: A Review.Animals : an open access journal from MDPI · 2020
    Review
  7. Interkingdom Cross-Talk in Times of Stress:Frontiers in immunology · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Lena ReiskeDepartment of Behavioral Physiology of Livestock, Institute of Animal Science, University of Hohenheim, Garbenstr. 17, 70599 Stuttgart, Germany.
Sonja SchmuckerDepartment of Behavioral Physiology of Livestock, Institute of Animal Science, University of Hohenheim, Garbenstr. 17, 70599 Stuttgart, Germany.
Julia SteuberDepartment of Cellular Microbiology, Institute of Microbiology, University of Hohenheim, Garbenstr. 30, 70599 Stuttgart, Germany.ORCID 0000-0002-1747-2747
Volker StefanskiDepartment of Behavioral Physiology of Livestock, Institute of Animal Science, University of Hohenheim, Garbenstr. 17, 70599 Stuttgart, Germany. volker.stefanski@uni-hohenheim.de.
University of Hohenheim · DE

Funding

Deutsche Forschungsgemeinschaft STE 633/10-1
6 · The paper itself

Abstract

Stress hormones exert important modulating influences on the functionality of immune cells. Despite its major role as a livestock animal and its increasing use as an animal model, knowledge about this relationship in the domestic pig is rare. This study therefore aimed to characterize the effect of glucocorticoids and catecholamines on the proliferation and cytokine production of porcine peripheral blood mononuclear cells (PBMC). Blood was obtained from donor pigs equipped with indwelling catheters to exclude stress hormone exposition before in vitro testing. PBMC were stimulated in the presence of cortisol, adrenaline or noradrenaline at concentrations resembling low to high stress conditions. Proliferation was determined via

Indexed as

adrenalinecatecholaminescortisolcytokinesimmune systemlymphocytesnoradrenalinepigstress

Identifiers

PMID31408932
PMCPMC6720833
OpenAlexW2968921274

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.