Evidence map›Paper›PMID 31408488›Full record

Trial reportPloS one2019

Trajectories of functional impairment in homeless older adults: Results from the HOPE HOME study.

Rebecca T Brown, David Guzman, Lauren M Kaplan, Claudia Ponath, Christopher T Lee, Margot B Kushel

Abstract readClinical Trial
In one paragraph

Trial report in PloS one, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Rebecca T BrownDivision of Geriatrics, University of California San Francisco, San Francisco, California, United States of America.ORCID 0000-0001-7483-4137
David GuzmanDivision of General Internal Medicine, University of California San Francisco, San Francisco, California, United States of America.
Lauren M KaplanDivision of General Internal Medicine, University of California San Francisco, San Francisco, California, United States of America.
Claudia PonathDivision of General Internal Medicine, University of California San Francisco, San Francisco, California, United States of America.
Christopher T LeeResolve to Save Lives, New York, New York, United States of America.
Margot B KushelDivision of General Internal Medicine, University of California San Francisco, San Francisco, California, United States of America.

Funding

VARC CoreP30AG044281 · NIA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI KENNETH E. COVINSKY · 2013 to 2026
$19.9M
Clinical and Transtional Science InstituteKL2TR000143 · NCATS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI GRANDIS, JENNIFER RUBIN · 2012 to 2015
$11.9M
Aging Among the Homeless: Social Isolation, Function and Institutional CareR01AG041860 · NIA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Margot B Kushel · 2012 to 2026
$9.3M
Mentoring Researchers in Aging in Vulnerable PopulationsK24AG046372 · NIA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI KUSHEL, MARGOT B · 2015 to 2025
$1.9M
Epidemiology and Outcomes of Premature Geriatrics SyndromesK23AG045290 · NIA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI BROWN, REBECCA TYLER · 2014 to 2018
$882k
Improving Aging in Place for Older Adults Living in Subsidized HousingK76AG057016 · NIA · UNIVERSITY OF PENNSYLVANIA · PI BROWN, REBECCA TYLER · 2018 to 2020
$853k
NCATS NIH HHS KL2 TR000143NIA NIH HHS K23 AG045290NIA NIH HHS K24 AG046372NIA NIH HHS K76 AG057016NIA NIH HHS P30 AG044281NIA NIH HHS R01 AG041860
6 · The paper itself

Abstract

Difficulty performing activities of daily living ("functional impairment") is common in homeless adults aged 50 and older. However, little is known about the trajectory of these impairments, nor the extent to which these trajectories are similar to those of older adults in the general population. We identified trajectories of functional impairment in homeless adults aged 50 and older, and risk factors for differing trajectories. We conducted a prospective cohort study of 350 homeless adults, aged 50 and older, recruited via population-based sampling in Oakland, California and interviewed at 6-month intervals for up to 3 years. We assessed functional trajectories based on self-reported difficulty performing 5 activities of daily living. We used multivariable multinomial logistic regression to identify baseline risk factors for each trajectory. At baseline, participants' mean age was 58 years (SD, 5.3), 24.1% were women, 80.9% were African American, and 38.6% had difficulty performing 1 or more activities of daily living. We identified 4 distinct functional trajectories: minimal impairment in 136 participants (41.1%); persistent impairment in 81 (25.4%); partial improvement in 74 (23.5%); and decline in 28 (10.0%). Risk factors for persistent impairment included falls in the 6 months before baseline, depressive symptoms, and low physical performance. Although functional impairment improved in some homeless adults, it persisted or worsened in many others. These findings suggest that, similar to older adults in the general population, functional impairment among older homeless persons is not a transient phenomenon, but instead a chronic issue requiring long-term solutions.

Indexed as

Activities of Daily LivingDepressionIll-Housed PersonsSelf ReportAgedCaliforniaFemaleFollow-Up StudiesHumansMaleMiddle AgedProspective StudiesRisk Factors

Identifiers

PMID31408488
PMCPMC6692032

What OpenQuestion holds

Textmetadata
LicenceCC0
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.