Evidence map›Paper›PMID 31408345›Full record

ArticleLangmuir : the ACS journal of surfaces and colloids2019

Peptide-Induced Lipid Flip-Flop in Asymmetric Liposomes Measured by Small Angle Neutron Scattering.

Michael H L Nguyen, Mitchell DiPasquale, Brett W Rickeard, Milka Doktorova, Frederick A Heberle, Haden L Scott, Francisco N Barrera, Graham Taylor, Charles P Collier, Christopher B Stanley and 2 more

Open access · greenAbstract read
In one paragraph

Article in Langmuir : the ACS journal of surfaces and colloids, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 58 citations in OpenAlex.

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  6. Bilayer Charge Asymmetry and Oil Residues Destabilize Membranes upon Poration.Langmuir : the ACS journal of surfaces and colloids · 2024
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  18. A mini-review: mechanism of antimicrobial action and application of surfactin.World journal of microbiology & biotechnology · 2022
    Review
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  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 2 countries.

Michael H L NguyenDepartment of Chemistry and Biochemistry , University of Windsor , Windsor , N9B 3P4 ON Canada.
Mitchell DiPasqualeDepartment of Chemistry and Biochemistry , University of Windsor , Windsor , N9B 3P4 ON Canada.
Brett W RickeardDepartment of Chemistry and Biochemistry , University of Windsor , Windsor , N9B 3P4 ON Canada.
Milka DoktorovaDepartment of Integrative Biology and Pharmacology , University of Texas Health Science Center at Houston , Houston , Texas 77225 , United States.
Frederick A HeberleDepartment of Integrative Biology and Pharmacology , University of Texas Health Science Center at Houston , Houston , Texas 77225 , United States.ORCID 0000-0002-0424-3240
Haden L ScottCenter for Environmental Biotechnology , University of Tennessee , Knoxville , Tennessee 37996 , United States.
Francisco N BarreraDepartment of Biochemistry & Cellular and Molecular Biology , University of Tennessee , Knoxville , Tennessee 37996 , United States.
Graham TaylorThe Bredesen Center , University of Tennessee , Knoxville , Tennessee 37996 , United States.
Charles P CollierThe Bredesen Center , University of Tennessee , Knoxville , Tennessee 37996 , United States.ORCID 0000-0002-8198-793X
Christopher B StanleyNeutron Scattering Division , Oak Ridge National Laboratory , Oak Ridge , Tennessee 37831 , United States.ORCID 0000-0002-4226-7710
John KatsarasLarge Scale Structures Group , Oak Ridge National Laboratory , Oak Ridge , Tennessee 37831 , United States.
Drew MarquardtDepartment of Chemistry and Biochemistry , University of Windsor , Windsor , N9B 3P4 ON Canada.ORCID 0000-0001-6848-2497
University of Tennessee at Knoxville · USUniversity of Windsor · CAOak Ridge National Laboratory · USThe University of Texas Health Science Center at Houston · US

Funding

Transmembrane Peptides for Targeting Acidosis - Equipment SupplementR01GM120642 · NIGMS · UNIVERSITY OF TENNESSEE KNOXVILLE · PI BARRERA, FRANCISCO NICOLAS · 2016 to 2020
$1.7M
NIGMS NIH HHS R01 GM120642
6 · The paper itself

Abstract

Despite the prevalence of lipid transbilayer asymmetry in natural plasma membranes, most biomimetic model membranes studied are symmetric. Recent advances have helped to overcome the difficulties in preparing asymmetric liposomes in vitro, allowing for the examination of a larger set of relevant biophysical questions. Here, we investigate the stability of asymmetric bilayers by measuring lipid flip-flop with time-resolved small-angle neutron scattering (SANS). Asymmetric large unilamellar vesicles with inner bilayer leaflets containing predominantly 1-palmitoyl-2-oleoyl-

Indexed as

LipidsLiposomesNeutron DiffractionParticle SizePeptidesScattering, Small AngleSurface PropertiesLipidsLiposomesPeptides

Identifiers

PMID31408345
PMCPMC7393738
OpenAlexW2966939253

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.