ReviewHippocampus2019
Neurons and networks in the entorhinal cortex: A reappraisal of the lateral and medial entorhinal subdivisions mediating parallel cortical pathways.
Review in Hippocampus, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 83 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
83 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Neuroanatomical and psychological considerations in temporal lobe epilepsy.Frontiers in neuroanatomy · 2022Pooled it
- Transcranial Alternating Current Stimulation Reduces Network Hypersynchrony and Persistent Vertigo.Neuromodulation : journal of the International Neuromodulation Society · 2021Trial
- An Update on the Model of Connectivity of the Hippocampal Formation (I): The Perforant Pathway to the Dentate Gyrus.Hippocampus · 2026Article
- NongeneticACS nano · 2026Article
- Persistently Increased Expression of PKMzeta and Unbiased Gene Expression Profiles Identify Hippocampal Molecular Traces of a Long-Term Active Place Avoidance Memory and "Shadow" Proteins.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Non-Canonical Subiculum Circuit Organization and Function.Hippocampus · 2026Review
- Can Music Therapy Improve Cognition in Dementia as Measured with Magnetoencephalography: A Hypothesis Study.Biomedicines · 2026Article
- Hierarchical Distribution of Reward Representation in the Cortical and Hippocampal Regions.eNeuro · 2026Article
- Peripheral inflammation mediates cognitive deficits in drug-naive schizophrenia through hippocampal-thalamo-visual circuitry dysfunction.Schizophrenia (Heidelberg, Germany) · 2026Article
- Engram cell vulnerability in neurodegeneration: from mechanistic insights to therapeutic horizons.Frontiers in aging neuroscience · 2026Review
- Landmark vector cells in the absence of visual input.iScience · 2025Article
- Differences in Cajal-Retzius Cell Density and Postnatal Persistence Across Cortical Areas Revealed by a Novel Intersectional Genetic Labeling Approach.The Journal of comparative neurology · 2025Article
- Organization and Community Usage of a Neuron Type Circuitry Knowledge Base of the Hippocampal Formation.Biomedicines · 2025Article
- Persistently increased expression of PKMzeta and unbiased gene expression profiles identify hippocampal molecular traces of a long-term active place avoidance memory and 'shadow' proteins.bioRxiv : the preprint server for biology · 2025Article
- Distinct brain regions map olfactory and visual spaces.bioRxiv : the preprint server for biology · 2025Article
- Entorhinal cortex layer III Adgrl2 expression controls topographical circuit connectivity required for sequence learning.Translational psychiatry · 2025Article
- Object-translocation induces event coding in the rat hippocampus.Communications biology · 2025Article
- Article
- The Inner Ear and Aging Brain: A Cross-Sectional Study of Vestibular Function and Morphometric Variations in the Entorhinal and Trans-Entorhinal Cortex.Journal of the Association for Research in Otolaryngology : JARO · 2025Article
- Dual inhibition of MAPK/ERK and BMP signaling induces entorhinal-like identity in mouse ESC-derived pallial progenitors.Stem cell reports · 2025Article
23 more citing papers are in PubMed but not listed here.
Corrections and comments
- Erratum issuedErratum.2020
Authors and funding
5 authors.
Funding
Abstract
In this review, we aim to reappraise the organization of intrinsic and extrinsic networks of the entorhinal cortex with a focus on the concept of parallel cortical connectivity streams. The concept of two entorhinal areas, the lateral and medial entorhinal cortex, belonging to two parallel input-output streams mediating the encoding and storage of respectively what and where information hinges on the claim that a major component of their cortical connections is with the perirhinal cortex and postrhinal or parahippocampal cortex in, respectively, rodents or primates. In this scenario, the lateral entorhinal cortex and the perirhinal cortex are connectionally associated and likewise the postrhinal/parahippocampal cortex and the medial entorhinal cortex are partners. In contrast, here we argue that the connectivity matrix emphasizes the potential of substantial integration of cortical information through interactions between the two entorhinal subdivisions and between the perirhinal and postrhinal/parahippocampal cortices, but most importantly through a new observation that the postrhinal/parahippocampal cortex projects to both lateral and medial entorhinal cortex. We suggest that entorhinal inputs provide the hippocampus with high-order complex representations of the external environment, its stability, as well as apparent changes either as an inherent feature of a biological environment or as the result of navigating the environment. This thus indicates that the current connectional model of the parahippocampal region as part of the medial temporal lobe memory system needs to be revised.
Indexed as
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.