ArticleCerebral cortex (New York, N.Y. : 1991)2020
Enhanced Bottom-Up and Reduced Top-Down fMRI Activity Is Related to Long-Lasting Nonreinforced Behavioral Change.
Article in Cerebral cortex (New York, N.Y. : 1991), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
9 citing papers in PubMed.
- Frontal tDCS reduces alcohol relapse rates by increasing connections from left dorsolateral prefrontal cortex to addiction networks.Brain stimulationTrial
- Mechanisms of Long-Term Nonexternally Reinforced Preference Change: Functional Connectivity Changes in a Longitudinal Functional MRI Study.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- Tuning the value of sweet food: Blocking sweet taste receptors increases the devaluation effect in a go/no-go task.Psychonomic bulletin & review · 2025Article
- Reactivating cue approached positive personality traits during sleep promotes positive self-referential processing.iScience · 2024Article
- Visual Selective Attention P300 Source in Frontal-Parietal Lobe: ERP and fMRI Study.Brain topography · 2022Article
- Memory for individual items is related to nonreinforced preference change.Learning & memory (Cold Spring Harbor, N.Y.) · 2021Article
- A Preferential Role for Ventromedial Prefrontal Cortex in Assessing "the Value of the Whole" in Multiattribute Object Evaluation.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2021Article
- The case against economic values in the orbitofrontal cortex (or anywhere else in the brain).Behavioral neuroscience · 2021Article
- Enhanced striatal and prefrontal activity is associated with individual differences in nonreinforced preference change for faces.Human brain mapping · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Behavioral change studies and interventions focus on self-control and external reinforcements to influence preferences. Cue-approach training (CAT) has been shown to induce preference changes lasting months by merely associating items with neutral cues and speeded responses. We utilized this paradigm to study neural representation of preferences and their modification without external reinforcements. We scanned 36 participants with fMRI during a novel passive viewing task before, after and 30 days following CAT. We preregistered the predictions that activity in memory, top-down attention, and value-processing regions will underlie preference modification. While most theories associate preferences with prefrontal regions, we found that "bottom-up" perceptual mechanisms were associated with immediate change, whereas reduced "top-down" parietal activity was related to long-term change. Activity in value-related prefrontal regions was enhanced immediately after CAT for trained items and 1 month after for all items. Our findings suggest a novel neural mechanism of preference representation and modification. We suggest that nonreinforced change of preferences occurs initially in perceptual representation of items, putatively leading to long-term changes in "top-down" processes. These findings offer implementation of bottom-up instead of top-down targeted interventions for long-lasting behavioral change.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.