ArticleThe Clinical journal of pain2019
A Subgroup of Chronic Low Back Pain Patients With Central Sensitization.
Article in The Clinical journal of pain, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06078033 (Efficacy of Mobilization With Movement on Conditioned Pain Modulation in Chronic Low Back Pain Patients), which is not on this map. Cited by 57 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Efficacy of Mobilization With Movement on Conditioned Pain Modulation in Chronic Low Back Pain Patients: A Randomized Controlled Trial
Who cites it
57 citing papers in PubMed, 99 citations in OpenAlex.
- Prevalence of Chronic Overlapping Pain Conditions in Participants With Chronic Low Back Pain Enrolled in a Pragmatic Trial of Mindfulness-Based Stress Reduction.European journal of pain (London, England) · 2025Trial
- Transcutaneous electrical nerve stimulation and heat to reduce pain in a chronic low back pain population: a randomized controlled clinical trial.Brazilian journal of physical therapyTrial
- Reduced lumbar myofascial mobility in chronic low back pain quantified using MR elastography-based slip interface imaging.European radiology experimental · 2026Article
- Altered somatosensory temporal discrimination in chronic non-specific low back pain patients with central sensitization-related features: a cross-sectional study.The Korean journal of pain · 2026Article
- Decoding pain in axial spondyloarthritis: Mechanisms, management, and future directions.Best practice & research. Clinical rheumatology · 2026Review
- Dorsal horn DCC amplification loop induced by endplate osteoclasts generates chronic nociplastic low back pain in male mice.Nature communications · 2026Article
- Article
- Central sensitization as a predictor of short-term postoperative outcomes in lumbar spinal stenosis: a prospective observational study.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026Observational
- Assessment of physical and psychological function factors and central sensitization-related symptoms associated with the Oswestry disability index in patients with lumbar spinal stenosis.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026Article
- Comparing Movement Patterns and Physical Function Between Chronic Low Back Pain Patients With Nociplastic and Nociceptive Pain Categories.JOR spine · 2026Article
- Comparing physical activity practice, pain and psychological characteristics in individuals with fibromyalgia and individuals with low back pain.Chiropractic & manual therapies · 2026Article
- Assessment of central pain sensitization in chronic low back pain and its utility in diagnosis and prediction of clinical severity.Scientific reports · 2026Article
- Prevalence and Associated Factors of Central Sensitization Among Patients with Chronic Low Back Pain at Mbarara Regional Referral Hospital, Uganda: A Cross-Sectional Study.Journal of pain research · 2026Article
- Immune-neural crosstalk in chronic low back pain: from intervertebral disc degeneration to pain sensitization.Frontiers in immunology · 2026Review
- Effects of a Multidimensional Exercise and Mindfulness Approach Targeting Physical, Psychological, and Functional Outcomes: Protocol for the BACKFIT Randomized Controlled Trial with an Active Control Group.Healthcare (Basel, Switzerland) · 2025Article
- Quantitative sensory testing for pain: What exactly are we measuring?Current opinion in psychology · 2025Review
- Is the Central Sensitization in Chronic Nonspecific Low Back Pain Structural Phenomenon or Psychological Reaction? A Narrative Review.Journal of clinical medicine · 2025Review
- Fibromyalgia is associated with increased odds of prior pain-precipitated relapse among non-treatment-seeking individuals with opioid use disorder.Annals of medicine · 2024Article
- Spinal pain prevalence and associated determinants: A population-based study using the National Survey for Wales.Physiological reports · 2024Article
- What are the functional and clinical characteristics shared by fibromyalgia and low back pain? A scoping review.BMC rheumatology · 2024Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundOur knowledge of central sensitization (CS) in chronic low back pain (CLBP) is limited. 2011 fibromyalgia criteria and severity scales (2011 FM survey) have been used to determine FM positive as a surrogate of CS. The major features of CS including widespread hyperalgesia and dysfunction of the descending inhibitory pathways can be identified by pressure pain threshold (PPT) and conditioned pain modulation (CPM) tests. The purpose of the study was to examine neurophysiological characteristics and psychosocial symptoms in a subgroup of FM-positive CLBP compared with FM-negative CLBP patients.
methodsA total of 46 participants with CLBP and 22 pain-free controls completed outcome measures of the 2011 FM survey, PPT and CPM tests, and psychosocial questionnaires. Differences between FM-positive and FM-negative CLBP participants on these measures and correlations were analyzed.
resultsThe 2011 FM survey identified 22 (48%) participants with CLBP as FM positive. FM-positive CLBP participants showed lower PPT values of the thumbnail (P=0.011) and lower back (P=0.003), lower CPM values of the thumbnail (P=0.002), and more severe pain catastrophizing, anxiety, and depression symptoms (P<0.05) than FM-negative CLBP participants. The 2011 FM scores were significantly correlated with the PPT and CPM values of the thumbnail and with psychosocial symptoms (P<0.001). DISCUSSION: Our findings suggest a subgroup of CLBP patients exhibiting with signs and symptoms of CS. Associations between subjective and objective CS measures indicate that the 2011 FM survey can be utilized to identify the presence of CS in CLBP in clinical practice.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.