ArticleThe neuroradiology journal2019
Targeting of the dentato-rubro-thalamic tract for MR-guided focused ultrasound treatment of essential tremor.
Article in The neuroradiology journal, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 4 of them syntheses that pooled it.
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Who cites it
19 citing papers in PubMed, 4 syntheses or guidelines pooled it, 32 citations in OpenAlex.
- Enhancing precision in MRgFUS for tremor treatment: a systematic review of tractography-based VIM targeting approaches.Neurosurgical review · 2025Pooled it
- Efficacy and Safety of Magnetic Resonance-Guided Focused Ultrasound Thalamotomy in Essential Tremor: A Systematic Review and Metanalysis.Movement disorders : official journal of the Movement Disorder Society · 2025Pooled it
- Magnetic resonance-guided focused ultrasound treatment for essential tremor shows sustained efficacy: a meta-analysis.Neurosurgical review · 2022Pooled it
- Outcome and Complications of MR Guided Focused Ultrasound for Essential Tremor: A Systematic Review and Meta-Analysis.Frontiers in neurology · 2021Pooled it
- Rescue deep brain stimulation for recurrent essential tremor after ventral intermediate nucleus thalamotomy: illustrative cases.Journal of neurosurgery. Case lessons · 2026Article
- Conserved fiber topography of the anterior limb of the internal capsule in treatment-resistant psychiatric patients.bioRxiv : the preprint server for biology · 2026Article
- Personalized tremor control targeting for MR-guided focused ultrasound using tractography.Brain communications · 2026Article
- The Results of a 12-Month Open-Label Follow-Up Study with MRI Monitoring of Patients with Parkinson's Disease After MRI-Guided FUS.Journal of clinical medicine · 2025Article
- Optimal focused ultrasound lesion location in essential tremor.Science advances · 2025Article
- Quantitative Tractography-Based Evaluations in Essential Tremor Patients after MRgFUS Thalamotomy.Movement disorders clinical practice · 2024Article
- Evaluation of Cerebral Volume Changes in Patients with Tremor Treated by MRgFUS Thalamotomy.Life (Basel, Switzerland) · 2022Article
- Essential Tremor-Do We Have Better Therapeutics? A Review of Recent Advances and Future Directions.Current neurology and neuroscience reports · 2022Review
- A detailed analysis of anatomical plausibility of crossed and uncrossed streamline rendition of the dentato-rubro-thalamic tract (DRT(T)) in a commercial stereotactic planning system.Acta neurochirurgica · 2021Article
- Comprehensive Evaluation of Factors Affecting Tremor Relapse after MRgFUS Thalamotomy: A Case-Control Study.Brain sciences · 2021Article
- Comparative evaluation of tractography-based direct targeting and atlas-based indirect targeting of the ventral intermediate (Vim) nucleus in MRgFUS thalamotomy.Scientific reports · 2021Article
- Resting State Functional Connectivity Signatures of MRgFUS Vim Thalamotomy in Parkinson's Disease: A Preliminary Study.Frontiers in neurology · 2021Article
- Clinical Characteristics of Patients with Gait Instability after MR-Guided Focused Ultrasound Thalamotomy.Tremor and other hyperkinetic movements (New York, N.Y.) · 2021Article
- Improved Vim targeting for focused ultrasound ablation treatment of essential tremor: A probabilistic and patient-specific approach.Human brain mapping · 2020Article
- MRI and tractography techniques to localize the ventral intermediate nucleus and dentatorubrothalamic tract for deep brain stimulation and MR-guided focused ultrasound: a narrative review and update.Neurosurgical focus · 2020Article
Corrections and comments
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundMagnetic resonance-guided focused ultrasound ablation of the thalamic ventral intermediate nucleus is a safe and effective treatment for medically refractory essential tremor. However, indirect targeting of the ventral intermediate nucleus using stereotactic coordinates from normal neuroanatomy can be inefficient. We therefore evaluated the feasibility of supplementing this method with direct targeting of the dentato-rubro-thalamic tract.
methodsWe retrospectively identified four patients undergoing magnetic resonance-guided focused ultrasound ablation for essential tremor in which preoperative diffusion tractography imaging of the dentato-rubro-thalamic tract was fused with T2 weighted-imaging and utilized for intra-procedural targeting. The size and location of the dentato-rubro-thalamic tract and 24-hour lesion, as well as the center of the stereotactic coordinates, was evaluated. Finally, the amount of overlap between the dentato-rubro-thalamic tract and the lesion was calculated.
resultsThe 24-hour lesion size was homogeneous in the cohort (mean 31.3 mm
conclusionDirect targeting of the dentato-rubro-thalamic tract using diffusion tractography imaging fused to T2 weighted-imaging may be a useful strategy for focused ultrasound treatment of essential tremor. Further investigation of the technique is warranted.
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