Evidence map›Paper›PMID 31407653›Full record

Trial reportThe American journal of tropical medicine and hygiene2019

Five-Year Impact of Different Multi-Year Mass Drug Administration Strategies on Childhood

Ye Shen, Ryan E Wiegand, Annette Olsen, Charles H King, Nupur Kittur, Sue Binder, Feng Zhang, Christopher C Whalen, William Evan Secor, Susan P Montgomery and 5 more

Registry-linked trialOpen access · hybridAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in The American journal of tropical medicine and hygiene, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07754617 (An RCT to Evaluate Different Treatment Approaches to Mitigate the Progression of Schistosomiasis Related Hepatic Fibrosis), which is not on this map. Cited by 13 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 2 pooled it
2.4field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07754617 phase2 / phase3not yet recruitingnot on this mapstarted 2026, after this paper: background citation

An RCT to Evaluate Different Treatment Approaches to Mitigate the Progression of Schistosomiasis Related Hepatic Fibrosis

TypeinterventionalSponsorRhode Island HospitalRan2026 to 2029Enrolled600ConditionsSchistosomiasis, Schistosoma Mansoni, Liver Fibrosis, Portal HypertensionArmsPraziquantel 40 mg/kg per dose given once annually, Praziquantel 40 mg/kg given three times per year
3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 2 syntheses or guidelines pooled it, 19 citations in OpenAlex.

  1. Pooled it
  2. SCORE Studies on the Impact of Drug Treatment on Morbidity due toThe American journal of tropical medicine and hygiene · 2020
    Pooled it
  3. Trial
  4. Trial
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Optimizing Delivery of Mass Drug Administration for Schistosomiasis.The American journal of tropical medicine and hygiene · 2019
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

15 authors at 7 institutions in 5 countries.

Ye ShenDepartment of Epidemiology & Biostatistics, University of Georgia, Athens, Georgia.
Ryan E WiegandUniversity of Basel, Basel, Switzerland.
Annette OlsenSection for Parasitology and Aquatic Pathobiology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Charles H KingSchistosomiasis Consortium for Operational Research and Evaluation, Center for Tropical and Emerging Global Diseases, University of Georgia, Athens, Georgia.
Nupur KitturSchistosomiasis Consortium for Operational Research and Evaluation, Center for Tropical and Emerging Global Diseases, University of Georgia, Athens, Georgia.
Sue BinderSchistosomiasis Consortium for Operational Research and Evaluation, Center for Tropical and Emerging Global Diseases, University of Georgia, Athens, Georgia.
Feng ZhangDepartment of Epidemiology & Biostatistics, University of Georgia, Athens, Georgia.
Christopher C WhalenDepartment of Epidemiology & Biostatistics, University of Georgia, Athens, Georgia.
William Evan SecorParasitic Diseases Branch, Division of Parasitic Diseases and Malaria, Centers for Disease Control and Prevention, Atlanta, Georgia.
Susan P MontgomeryParasitic Diseases Branch, Division of Parasitic Diseases and Malaria, Centers for Disease Control and Prevention, Atlanta, Georgia.
Pauline N M MwinziCentre for Global Health Research, Kenya Medical Research Institute, Kisumu, Kenya.
Pascal MagnussenCentre for Medical Parasitology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Safari Kinung'hiMwanza Research Centre, National Institute for Medical Research, Mwanza, Tanzania.
Carl H CampbellSchistosomiasis Consortium for Operational Research and Evaluation, Center for Tropical and Emerging Global Diseases, University of Georgia, Athens, Georgia.
Daniel G ColleyDepartment of Microbiology, University of Georgia, Athens, Georgia.
University of Georgia · USDivision of Parasitic Diseases and Malaria · USUniversity of Copenhagen · DKCenter for Global Health · USKenya Medical Research Institute · KENational Institute for Medical Research · TZSwiss Tropical and Public Health Institute · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The WHO recommends mass treatment with praziquantel as the primary approach for

Indexed as

AnthelminticsChildCohort StudiesDrug Administration ScheduleFecesFemaleGeographyHumansKenyaMaleMass Drug AdministrationPraziquantelPrevalenceSchistosomiasis mansoniSchoolsTanzaniaAnthelminticsPraziquantel

Identifiers

PMID31407653
PMCPMC6896894
OpenAlexW2966986624

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.