Observational studyCancer medicine2019
Cognitive and motor aspects of cancer-related fatigue.
Observational study in Cancer medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed, 1 synthesis or guideline pooled it, 36 citations in OpenAlex.
- Cancer-related fatigue during treatment with neoadjuvant and/or adjuvant immune checkpoint inhibitors: a systematic review and meta-analysis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026Pooled it
- Herbal and pharmacological treatments in cancer-related fatigue.Translational gastroenterology and hepatology · 2026Article
- Network analysis of fatigue symptoms in Chinese patients with advanced cancer.Asia-Pacific journal of oncology nursing · 2025Article
- Objective measurement of cancer-related fatigue.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025Review
- Chronic Fatigue in Cancer Survivorship: Psychiatry Versus Oncology or Psychiatry with Oncology?Current oncology reports · 2025Review
- Incidence and predictors of immune checkpoint inhibitor treatment-related cognitive impairment in a racial and ethnic diverse population.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025Article
- Fatigue Level Associated with Quality of Life for Prostate Cancer Patients: Results from the All of Us Research Program.Cancers · 2025Article
- Transcriptomic Profiles and Functional Correlates of Cancer-Related Fatigue: A Cross-Sectional Study in Women Undergoing Cancer Treatment.European journal of cancer care · 2025Article
- Circadian Rhythm and Physical Fatigue Separately Influence Cognitive and Physical Performance in Amateur Athletes.Journal of functional morphology and kinesiology · 2024Article
- Fatigue in Prostate Cancer: A Roundtable Discussion and Thematic Literature Review.European urology open science · 2024Review
- Multidisciplinary analysis of cancer-related fatigue at the time of diagnosis: preliminary results of the BIOCARE FActory cohort.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024Article
- Cancer: A model topic for misinformation researchers.Current opinion in psychology · 2024Review
- Harnessing the Systemic Biology of Functional Decline and Cachexia to Inform more Holistic Therapies for Incurable Cancers.Cancers · 2024Review
- Longitudinal Associations Between Higher Self-Reported Energy, Gait Speed, and Cognition in Older Adults With Fatigue.The journals of gerontology. Series A, Biological sciences and medical sciences · 2023Article
- Absence of risk of sarcopenia protects cancer patients from fatigue.European journal of clinical nutrition · 2022Article
- A Critical Review of Symptom Management Nursing Science on HIV-Related Fatigue and Sleep Disturbance.International journal of environmental research and public health · 2021Review
- Usability and Effectiveness of Immersive Virtual Grocery Shopping for Assessing Cognitive Fatigue in Healthy Controls: Protocol for a Randomized Controlled Trial.JMIR research protocols · 2021Article
- Inflammation plays a causal role in fatigue-like behavior induced by pelvic irradiation in mice.Brain, behavior, & immunity - health · 2021Article
- Plasma metabolomic profile associated with fatigue in cancer patients.Cancer medicine · 2021Article
- Association of handgrip strength and endurance with body composition in head and neck cancer patients.Journal of family medicine and primary care · 2021Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundCancer-related fatigue (CRF) is a debilitating symptom frequently reported by patients during and after treatment for cancer. CRF is a multidimensional experience and is often solely assessed by self-report measures. The goal of the study is to examine the physical and cognitive aspects of self-reported CRF using a cognitive function test and a physical fatigue index in order to provide objective measures that can characterize the CRF phenotype.
methodsA total of 59 subjects with nonmetastatic prostate cancer receiving external beam radiation therapy were included in the study. Fatigue was measured using the Functional Assessment of Cancer Therapy-Fatigue (FACT-F) questionnaire. Cognitive characteristics of CRF was measured using the Stroop Color-Word Interference computerized test and the motor aspect of fatigue was measured using the static fatigue test using a handgrip dynamometer.
findingsFunctional Assessment of Cancer Therapy-Fatigue scores significantly correlated with the Stroop Interference score, but not performance accuracy in all test conditions. Fatigued subjects exhibited a more rapid decline to 50% of maximal strength and increased static fatigue index in the handgrip test, whereas maximal grip strength was not affected.
conclusionsThe results suggest that CRF exhibits both cognitive and physical characteristics. Subjective fatigue was associated with increased time required to overcome cognitive interference, but not cognitive performance accuracy. Fatigued patients exhibited decreased physical endurance and the ability to sustain maximal strength over time. These objective measures may serve as valuable tools for clinicians to detect cognitive and physical impairment associated with CRF.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.