Evidence map›Paper›PMID 31407512›Full record

ArticleInternational wound journal2019

Does closed incision negative wound pressure therapy in non-traumatic major lower-extremity amputations improve survival rates?

Charlotte P Stenqvist, Camilla T Nielsen, George M Napolitano, Bo M Larsen, Mitchell J Flies, Ditte C Brander, Elsebeth Lynge, Per Pallesen

Open access · greenAbstract read
In one paragraph

Article in International wound journal, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.7field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
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  3. Review
  4. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Charlotte P StenqvistDepartment of Orthopedic Surgery, Nykoebing Falster Hospital, Nykoebing Falster, Denmark.
Camilla T NielsenDepartment of Orthopedic Surgery, Nykoebing Falster Hospital, Nykoebing Falster, Denmark.
George M NapolitanoDepartment of Public Health, University of Copenhagen, Copenhagen, Denmark.
Bo M LarsenDepartment of Orthopedic Surgery, Nykoebing Falster Hospital, Nykoebing Falster, Denmark.
Mitchell J FliesDepartment of Orthopedic Surgery, Nykoebing Falster Hospital, Nykoebing Falster, Denmark.
Ditte C BranderDepartment of Orthopedic Surgery, Nykoebing Falster Hospital, Nykoebing Falster, Denmark.
Elsebeth LyngeCentre for Epidemiological Research, Nykoebing Falster Hospital, University of Copenhagen, Nykoebing Falster, Denmark.
Per PallesenDepartment of Orthopedic Surgery, Nykoebing Falster Hospital, Nykoebing Falster, Denmark.
Sjællands Universitetshospital, Nykøbing F. · DKUniversity of Copenhagen · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Closed incision negative pressure wound therapy (CINPWT) has been shown to be clinically effective compared with the traditional gauze dressing, reducing surgical site infections and wound complications. We evaluated the effect of CINPWT compared with gauze dressing on the need for revision surgery and survival after non-traumatic major lower amputation. We included 309 patients undergoing 403 major lower amputations in a retrospective study from January 1, 2010 to November 23, 2017. A total of 139 patients received CINPWT, and 170 patients received stump bandage. There was no statistically significant difference between the two groups regarding the need for revision surgery (P = .45). Fourteen stump bandage patients and 15 CINPWT patients died in hospital (P = .57). One year after amputation, 55 CINPWT patients and 66 stump bandage patients had died (P = .82). Survival probabilities adjusted for age and gender 2 years after amputation were .52 (.43-.61) and .49 (.42-.58), respectively, and 3 years after amputation were .36 (.25-.50) and .39 (.32-.47), respectively. We also found no significant difference in the need for revision surgery in survival probabilities up till 3 years after amputation between patients treated with CINPWT and patients treated with gauze bandage postoperatively.

Indexed as

AgedAmputation StumpsAmputation, SurgicalBandagesCohort StudiesDenmarkFemaleHumansLower ExtremityMaleMiddle AgedNegative-Pressure Wound TherapyPrognosisReoperationRetrospective StudiesRisk Assessmentamputationdiabetesinfection

Identifiers

PMID31407512
PMCPMC7948641
OpenAlexW2967831877

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.