Evidence map›Paper›PMID 31407478›Full record

ArticleRespirology (Carlton, Vic.)2020

Clinical outcomes and survival following lung transplantation in patients with pulmonary Langerhans cell histiocytosis.

Nikolai Wajda, Zheng Zhu, Roman Jandarov, Daniel F Dilling, Nishant Gupta

Open access · greenAbstract read
In one paragraph

Article in Respirology (Carlton, Vic.), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Clinical analysis for 15 patients with pulmonary Langerhans cell histiocytosis and literature review.Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2022
    Review
  5. Lung transplantation for interstitial lung disease.European respiratory review : an official journal of the European Respiratory Society · 2021
    Review
  6. Review
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Nikolai WajdaDivision of Pulmonary, Critical Care, and Sleep Medicine, University of Cincinnati Medical Center, Cincinnati, OH, USA.
Zheng ZhuDepartment of Environmental Health, University of Cincinnati, Cincinnati, OH, USA.
Roman JandarovDepartment of Environmental Health, University of Cincinnati, Cincinnati, OH, USA.
Daniel F DillingDivision of Pulmonary and Critical Care, Loyola University Chicago, Stritch School of Medicine, Maywood, IL, USA.
Nishant GuptaDivision of Pulmonary, Critical Care, and Sleep Medicine, University of Cincinnati Medical Center, Cincinnati, OH, USA.ORCID 0000-0001-9112-1315
Cincinnati Health Department · USVeterans Health Administration · USLoyola University Chicago · US

Funding

Resveratrol and Sirolimus in LAM Trial (RESULT)R34HL138235 · NHLBI · UNIVERSITY OF CINCINNATI · PI GUPTA, NISHANT · 2017 to 2019
$712k
NHLBI NIH HHS R34 HL138235NHLBI NIH HHS R34HL138235
6 · The paper itself

Abstract

BACKGROUND AND

objectiveDisease-specific outcomes following lung transplantation (LT) in patients with pulmonary Langerhans cell histiocytosis (PLCH) are not well established. We queried the Organ Procurement and Transplantation Network database to identify adult PLCH patients who had undergone LT in the United States.

methodsOverall survival data were analysed with Kaplan-Meier curves. Cox proportional hazard model was used to determine the effect of demographic, clinical and physiological variables on post-transplant survival.

resultsA total of 87 patients with PLCH underwent LT in the United States between October 1987 and June 2017, accounting for 0.25% of the total LT during this period. The mean age at LT for PLCH patients was 49 years (range: 19-67 years), with a near equal gender distribution. Bilateral sequential LT was performed in 71 patients (82%). Pulmonary hypertension was present in 85% of patients, with a mean pulmonary artery pressure of 38.5 ± 14.1 mm Hg. The mean pre-transplant forced expiratory volume in 1 s (FEV

conclusionPost-LT survival in patients with PLCH is similar to patients with other lung diseases and is significantly affected by patient gender.

Indexed as

AdultAgedBilirubinCohort StudiesCreatinineFemaleForced Expiratory VolumeHistiocytosis, Langerhans-CellHumansHypertension, PulmonaryLung TransplantationMaleMiddle AgedProportional Hazards ModelsRespiratory Function TestsSex FactorsBilirubinCreatininebronchiolitis obliteransLangerhans cell histiocytosismortalitypulmonary hypertensionpulmonary Langerhans cell histiocytosis

Identifiers

PMID31407478
PMCPMC8643712
OpenAlexW2966980543

What OpenQuestion holds

Textmetadata
LicenceTDM
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.