GuidelineNeurogastroenterology and motility2020
The international anorectal physiology working group (IAPWG) recommendations: Standardized testing protocol and the London classification for disorders of anorectal function.
Guideline in Neurogastroenterology and motility, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04949646 (Intraoperative Neuromonitoring of Pelvic Autonomous Nerve Plexus During Total Mesorectal Excision), which is not on this map. Cited by 140 papers, 8 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Intraoperative Neuromonitoring of Pelvic Autonomous Nerve Plexus During Total Mesorectal Excision
Who cites it
140 citing papers in PubMed, 8 syntheses or guidelines pooled it, 299 citations in OpenAlex.
- The Italian Unitary Society of Colon-Proctology (SIUCP: Società Italiana Unitaria di Colonproctologia) guidelines for the management of obstructed and ineffective defecation syndrome.Annals of coloproctology · 2026Guideline
- [Seoul Consensus on Clinical Practice Guidelines for Functional Constipation].The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi · 2025Guideline
- How Can We Treat If We Do Not Measure: A Systematic Review of Neurogenic Bowel Objective Measures.Topics in spinal cord injury rehabilitation · 2024Pooled it
- Evaluating lleal Pouch Anal Anastomosis Function: Time to Expand Our ARM-amentarium.Inflammatory bowel diseases · 2023Pooled it
- Systematic review and meta-analysis of anal motor and rectal sensory dysfunction in male and female patients undergoing anorectal manometry for symptoms of faecal incontinence.Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland · 2022Pooled it
- Anorectal manometry to diagnose dyssynergic defecation: Systematic review and meta-analysis of diagnostic test accuracy.Neurogastroenterology and motility · 2021Pooled it
- The international anorectal physiology working group (IAPWG) recommendations: Standardized testing protocol and the London classification for disorders of anorectal function.Neurogastroenterology and motility · 2020Guideline
- Recommendations for the reopening and activity resumption of the neurogastroenterology units in the face of the COVID-19 pandemic. Position of the Sociedad Latinoamericana de Neurogastroenterología.Revista de gastroenterologia de Mexico (English)Guideline
- Correlation of Digital Rectal Examination and Anorectal Manometry with Patient-Reported Outcomes Among Women with Fecal Incontinence.International urogynecology journal · 2024Trial
- Development of a Simple, Point-of-Care Device to Test Anorectal Function in Patients with Constipation: Randomized Clinical Trial.Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association · 2023Trial
- Ameliorating effects and mechanisms of transcutaneous auricular vagal nerve stimulation on abdominal pain and constipation.JCI insight · 2021Trial
- Novel Fecobionics Defecatory Function Testing.Clinical and translational gastroenterology · 2019Trial
- Artificial Intelligence in High-resolution Anorectal Manometry: Current Applications and Future Directions.Current gastroenterology reports · 2026Review
- Diagnostic Value of the Anal Endoluminal Functional Luminal Imaging Probe for the Diagnosis of Anismus: An Exploratory Study.Neurogastroenterology and motility · 2026Article
- High-resolution anorectal manometry in children with constipation-associated fecal incontinence.European journal of pediatrics · 2026Article
- The Utility of the Functional Sphincter Area: A Novel Functional Lumen Imaging Probe Parameter for the Assessment of Anal Sphincter Structure and Function in Fecal Incontinence.Journal of neurogastroenterology and motility · 2026Article
- Short and long-term outcomes of anorectal biofeedback therapy in patients with functional defecation disorders: Efficacy and predictors of response.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2026Article
- Recurrence After Rectopexy: Insights From Magnetic Resonance Defecography.Diseases of the colon and rectum · 2026Article
- Sensation of Incomplete Evacuation in Patients With Fecal Incontinence: A Cross-Sectional Study of a Tertiary Referral Cohort.Neurogastroenterology and motility · 2026Article
- Methane Trajectory Phenotypes on Glucose Breath Testing Are Associated With Slow Colonic Transit: A Group-Based Trajectory Modeling Analysis.Neurogastroenterology and motility · 2026Article
80 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
30 authors at 20 institutions in 12 countries.
Funding
Abstract
backgroundThis manuscript summarizes consensus reached by the International Anorectal Physiology Working Group (IAPWG) for the performance, terminology used, and interpretation of anorectal function testing including anorectal manometry (focused on high-resolution manometry), the rectal sensory test, and the balloon expulsion test. Based on these measurements, a classification system for disorders of anorectal function is proposed.
methodsTwenty-nine working group members (clinicians/academics in the field of gastroenterology, coloproctology, and gastrointestinal physiology) were invited to six face-to-face and three remote meetings to derive consensus between 2014 and 2018. KEY RECOMMENDATIONS: The IAPWG protocol for the performance of anorectal function testing recommends a standardized sequence of maneuvers to test rectoanal reflexes, anal tone and contractility, rectoanal coordination, and rectal sensation. Major findings not seen in healthy controls defined by the classification are as follows: rectoanal areflexia, anal hypotension and hypocontractility, rectal hyposensitivity, and hypersensitivity. Minor and inconclusive findings that can be present in health and require additional information prior to diagnosis include anal hypertension and dyssynergia. CONCLUSIONS AND INFERENCES: This framework introduces the IAPWG protocol and the London classification for disorders of anorectal function based on objective physiological measurement. The use of a common language to describe results of diagnostic tests, standard operating procedures, and a consensus classification system is designed to bring much-needed standardization to these techniques.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.