Evidence map›Paper›PMID 31407140›Full record

ReviewHeart failure reviews2020

β-Adrenergic receptor, an essential target in cardiovascular diseases.

Daniel Chikere Ali, Muhammad Naveed, Andrew Gordon, Fatima Majeed, Muhammad Saeed, Michael I Ogbuke, Muhammad Atif, Hafiz Muhammad Zubair, Li Changxing

Abstract readReview
PubMed Publisher
In one paragraph

Review in Heart failure reviews, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed, 1 pooled it
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

46 citing papers in PubMed, 1 synthesis or guideline pooled it, 76 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 2 countries.

Daniel Chikere AliDepartment of Microbiological and Biochemical Pharmacy, School of Life Science, China Pharmaceutical University, Nanjing, 210009, Jiangsu Province, People's Republic of China.
Muhammad NaveedDepartment of Clinical Pharmacology, School of Pharmacy, Nanjing Medical University, 211166, Nanjing, Jiangsu Province, People's Republic of China.ORCID 0000-0002-2193-9266
Andrew GordonDepartment of Pharmacognosy, School of Pharmacy, China Pharmaceutical University, Nanjing, 210009, Jiangsu Province, People's Republic of China.
Fatima MajeedDepartment of Nutrition and Food Hygiene, School of Public Health, Nanjing Medical University, Nanjing, 211166, Jiangsu Province, People's Republic of China.
Muhammad SaeedFaculty of Animal Production and Technology, The Cholistan University of Veterinary and Animal Sciences, Bahawalpur, 6300, Punjab Province, Pakistan.
Michael I OgbukeDepartment of Pharmacy, School of Pharmacy, China Pharmaceutical University, Nanjing, Jiangsu Province, 210009, People's Republic of China.
Muhammad AtifFaculty of Pharmacy and Alternative Medicine, The Islamia University of Bahawalpur, Bahawalpur, 63100, Punjab Province, Pakistan.
Hafiz Muhammad ZubairDepartment of Pharmacology, School of Basic Medical Sciences, Nanjing Medical University, Nanjing, 211166, Jiangsu Province, People's Republic of China.
Li ChangxingDepartment of Human Anatomy, Medical College of Qinghai University, Xining, 810000, Qinghai Province, People's Republic of China. lcx1535@163.com.
China Pharmaceutical University · CNNanjing Medical University · CNIslamia University of Bahawalpur · PKQinghai University · CNUniversity of Veterinary and Animal Sciences · PK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

β-Adrenergic receptors (βARs) belong to a large family of cell surface receptors known as G protein-coupled receptors (GPCRs). They are coupled to Gs protein (Gαs) for the activation of adenylyl cyclase (AC) yielding cyclic AMP (

Indexed as

AnimalsBiomarkersCardiovascular DiseasesDisease ProgressionHumansMyocardiumPrognosisReceptors, Adrenergic, betaBiomarkersReceptors, Adrenergic, betaAdenylyl cyclaseCardiovascular diseaseCatecholaminesGPCRHeart failureβ-Adrenergic receptor

Identifiers

PMID31407140
OpenAlexW2967630615

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.