ArticleJGH open : an open access journal of gastroenterology and hepatology2019
Noninvasive estimation of intravascular volume status in cirrhosis by dynamic size and collapsibility indices of the inferior vena cava using bedside echocardiography.
Article in JGH open : an open access journal of gastroenterology and hepatology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 16 papers.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Study of Coagulation Profile and Role of Heparin-like Effect in Patients With COVID-19
To Compare the Effectiveness of Various Methods of Estimating Volume Resuscitation in Patients With Cirrhosis With Sepsis Induced Hypotension
Who cites it
16 citing papers in PubMed.
- Development and validation of a proposed rule for estimating central venous pressure from inferior vena cava dynamics: a clinical prediction model study.Journal of anesthesia, analgesia and critical care · 2026Article
- Treating Hepatorenal Syndrome in the Current Era.Journal of the American Society of Nephrology : JASN · 2026Review
- The Kidney in the Shadow of Cirrhosis: A Critical Review of Renal Failure.Biomedicines · 2025Review
- Point-of-care ultrasound of the inferior vena cava for intravascular volume assessment during intravenous albumin infusion in patients with cirrhosis.JHEP reports : innovation in hepatology · 2025Article
- Understanding acute kidney injury in cirrhosis: Current perspective.World journal of hepatology · 2025Review
- Influence of Increased Intra-Abdominal Pressure on the Validity of Ultrasound-Derived Inferior Vena Cava Measurements for Estimating Central Venous Pressure.Journal of clinical medicine · 2025Article
- Management of the acute on chronic liver failure in the intensive care unit.Liver international : official journal of the International Association for the Study of the Liver · 2025Review
- Point-of-Care Ultrasound in Nephrology: Beyond Kidney Ultrasound.Diagnostics (Basel, Switzerland) · 2025Review
- Article
- Acute Kidney Injury in Liver Cirrhosis.Diagnostics (Basel, Switzerland) · 2023Review
- Review article: Practical considerations for fluid resuscitation in cirrhosis.Alimentary pharmacology & therapeutics · 2023Review
- Management of Decompensated Cirrhosis in the Surgical ICU: an American Association for the Surgery of Trauma Critical Care Committee Clinical Consensus Document.Trauma surgery & acute care open · 2022Article
- Review
- Echocardiography versus Bioimpedance in Evaluating Volume Status in Patients with Chronic Cardiorenal Syndrome: A Preliminary Study.Journal of cardiovascular echographyArticle
- Overview of Complications in Cirrhosis.Journal of clinical and experimental hepatologyReview
- Diagnosis and Management of Cirrhotic Cardiomyopathy.Journal of clinical and experimental hepatologyArticle
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND AND
aimEchocardiographic assessment of the inferior vena cava diameter (IVCD) and collapsibility index (IVCCI) is a noninvasive estimate of intravascular volume status (IVS) but requires validation for cirrhosis. We evaluated IVC dynamics in cirrhosis and correlated it with conventional tools such as central venous pressure (CVP), pulmonary capillary wedge pressure (PCWP), and right atrial pressure (RAP).
methodsA total of 673 consecutive cirrhotic patients were screened by echocardiography, and 125 patients underwent right heart catheterization with recording of hepatic venous pressure gradient (HVPG), RAP, pulmonary artery (PA) pressure, and PCWP. CVP data were available for 80 (64%) patients, and finally, 76 patients (84% male, 50% ethanol related, mean age 52.1 years, 57.8% with ascites) with complete data were enrolled.
resultsThe mean CVP measured was 12.8 ± 4.8 mmHg, and IVCCI was 29.5 ± 10.9%. The IVCD ranged from 0.97 to 2.26 cm and from 0.76 to 1.84 cm during expiration and inspiration, respectively, with a mean of 1.8 ± 0.9 cm. The mean IVCD correlated with RAP (
conclusionsIVCD and collapsibility index provides noninvasive IVS assessment, independent of HVPG or ascites, with the potential for calculating fluid requirements in cirrhosis.
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Registered trials
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