Evidence map›Paper›PMID 31406922›Full record

ArticleJGH open : an open access journal of gastroenterology and hepatology2019

Change in serum levels of inflammatory markers reflects response of percutaneous catheter drainage in symptomatic fluid collections in patients with acute pancreatitis.

Bipadabhanjan Mallick, Shallu Tomer, Sunil K Arora, Anupam Lal, Narendra Dhaka, Jayanta Samanta, Saroj K Sinha, Vikas Gupta, Thakur Deen Yadav, Rakesh Kochhar

Open access · goldAbstract read
In one paragraph

Article in JGH open : an open access journal of gastroenterology and hepatology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.0field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Review
  3. Percutaneous Biopsy and Drainage of the Pancreas.Seminars in interventional radiology · 2024
    Review
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Bipadabhanjan MallickDepartment of Gastroenterology Postgraduate Institute of Medical Education and Research Chandigarh India.ORCID https://orcid.org/0000-0001-8209-6947
Shallu TomerDepartment of Immunopathology Postgraduate Institute of Medical Education and Research Chandigarh India.
Sunil K AroraDepartment of Immunopathology Postgraduate Institute of Medical Education and Research Chandigarh India.
Anupam LalDepartment of Radiodiagnosis Postgraduate Institute of Medical Education and Research Chandigarh India.
Narendra DhakaDepartment of Gastroenterology Postgraduate Institute of Medical Education and Research Chandigarh India.
Jayanta SamantaDepartment of Gastroenterology Postgraduate Institute of Medical Education and Research Chandigarh India.
Saroj K SinhaDepartment of Gastroenterology Postgraduate Institute of Medical Education and Research Chandigarh India.ORCID https://orcid.org/0000-0001-8088-9935
Vikas GuptaDepartment of General Surgery Postgraduate Institute of Medical Education and Research Chandigarh India.
Thakur Deen YadavDepartment of General Surgery Postgraduate Institute of Medical Education and Research Chandigarh India.
Rakesh KochharDepartment of Gastroenterology Postgraduate Institute of Medical Education and Research Chandigarh India.ORCID https://orcid.org/0000-0002-4077-6474
Post Graduate Institute of Medical Education and Research · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPercutaneous catheter drainage (PCD) is used as the first step in the management of symptomatic fluid collections in patients with acute pancreatitis (AP). There are limited data on the effect of PCD on inflammatory markers.

aimTo study the effects of PCD on serum levels of C-reactive protein (CRP), IL-6, and IL-10 and its correlation with the outcome.

methodsConsecutive patients of AP with symptomatic fluid collections undergoing PCD were evaluated for serum levels of CRP, IL-6, and IL-10 before PCD and at 3 and 7 days after PCD. Resolution of organ failure (OF), sepsis, and pressure symptoms was considered to demonstrate the success of PCD. Changes in levels following PCD were correlated with outcome.

resultsIndications of PCD in 59 patients (age 38.9 ± 13.17 years, 49 male) were suspected/documented infected pancreatic necrosis (

conclusionPCD is associated with a significant decrease in CRP, IL-6, and IL-10 levels. Percentage decrease in IL-6 on day 3 and CRP on day 7 correlated with the outcome of patients managed with PCD.

Indexed as

acute pancreatitisC‐reactive proteininflammatory markersinterleukin‐10interleukin‐6interleukinspercutaneous catheter drainage

Identifiers

PMID31406922
PMCPMC6684513
OpenAlexW2921127856

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.