Evidence map›Paper›PMID 31406691›Full record

ArticleClinical and experimental vaccine research2019

Effect of simultaneous administration of foot-and-mouth disease (FMD) and anthrax vaccines on antibody response to FMD in sheep.

Can Çokçalışkan, Pelin Tuncer Göktuna, Tunçer Türkoğlu, Ergün Uzunlu, Ceylan Gündüzalp, Eylem Aras Uzun, Beyhan Sareyyüpoğlu, Ayça Kürkçü, Veli Gülyaz

Open access · diamondAbstract read
In one paragraph

Article in Clinical and experimental vaccine research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Anthrax: A narrative review.New microbes and new infections · 2024
    Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 2 countries.

Can ÇokçalışkanRepublic of Turkey Ministry of Agriculture and Forestry, Institute of Foot and Mouth Disease (SAP), Ankara, Turkey.ORCID https://orcid.org/0000-0002-3839-0986
Pelin Tuncer GöktunaRepublic of Turkey Ministry of Agriculture and Forestry, Institute of Foot and Mouth Disease (SAP), Ankara, Turkey.ORCID https://orcid.org/0000-0002-7468-0155
Tunçer TürkoğluRepublic of Turkey Ministry of Agriculture and Forestry, Institute of Foot and Mouth Disease (SAP), Ankara, Turkey.ORCID https://orcid.org/0000-0002-6780-6186
Ergün UzunluRepublic of Turkey Ministry of Agriculture and Forestry, Institute of Foot and Mouth Disease (SAP), Ankara, Turkey.ORCID https://orcid.org/0000-0002-0509-7257
Ceylan GündüzalpRepublic of Turkey Ministry of Agriculture and Forestry, Institute of Foot and Mouth Disease (SAP), Ankara, Turkey.ORCID https://orcid.org/0000-0003-1282-6400
Eylem Aras UzunRepublic of Turkey Ministry of Agriculture and Forestry, Institute of Foot and Mouth Disease (SAP), Ankara, Turkey.ORCID https://orcid.org/0000-0001-5845-4791
Beyhan SareyyüpoğluRepublic of Turkey Ministry of Agriculture and Forestry, Institute of Foot and Mouth Disease (SAP), Ankara, Turkey.ORCID https://orcid.org/0000-0002-0279-1673
Ayça KürkçüRepublic of Turkey Ministry of Agriculture and Forestry, Institute of Foot and Mouth Disease (SAP), Ankara, Turkey.ORCID https://orcid.org/0000-0002-6411-917X
Veli GülyazRepublic of Turkey Ministry of Agriculture and Forestry, Institute of Foot and Mouth Disease (SAP), Ankara, Turkey.ORCID https://orcid.org/0000-0002-9089-919X
Ministry of Agriculture and Forestry · LA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeFoot-and-mouth disease (FMD) and anthrax are important diseases in sheep. Vaccination is a favorable strategy against both infections. Simultaneous administration of vaccines does generally not impede the immune responses of each other, although there are some exceptions, and it may help reduce the labor and costs of vaccination as well as distress on animals. Although oil adjuvant FMD vaccine has been tried with live anthrax vaccine in cattle, there are no reports on the simultaneous use of both vaccines in sheep. MATERIALS AND

methodsIn this study, FMD seronegative sheep were used to investigate the impact of the simultaneous vaccination of FMD and anthrax on FMD antibody titers of sheep. Virus neutralization test and liquid phase blocking enzyme-linked immunosorbent assay were used to determine the antibody response to the FMD vaccine.

resultsThe results demonstrated that both vaccines can be used simultaneously without any interference with the FMD response. Moreover, the simultaneous administration with anthrax vaccine had a stimulating effect on the early (day 7 post-vaccination) virus neutralization antibody response to the FMD vaccine.

conclusionThe simultaneous use of the FMD and anthrax vaccines did not hinder the response to the FMD vaccine in sheep.

Indexed as

AnthraxFoot-and-mouth diseaseSheepSimultaneous vaccinationVirus neutralization

Identifiers

PMID31406691
PMCPMC6689499
OpenAlexW2968286661

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.