Evidence map›Paper›PMID 31406349›Full record

Trial reportNature medicine2019

Gut microbiome alteration in MORDOR I: a community-randomized trial of mass azithromycin distribution.

T Doan, A Hinterwirth, L Worden, A M Arzika, R Maliki, A Abdou, S Kane, L Zhong, M E Cummings, S Sakar and 8 more

Registry-linked trialAbstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in Nature medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06358872 (Azithromycine Pour la Vie Des Enfants au Niger II), which is not on this map. Cited by 88 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
88citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06358872 phase4recruitingnot on this mapstarted 2024, after this paper: background citation

Azithromycine Pour la Vie Des Enfants au Niger II

TypeinterventionalSponsorUniversity of California, San FranciscoRan2024 to 2028Enrolled3,300,000ConditionsMortality, Antimicrobial ResistanceArmsAzithromycin for Oral Suspension
3 · Its place in the literature

Who cites it

88 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Trial
  5. Trial
  6. Trial
  7. Trial
  8. Trial
  9. Trial
  10. Effect of one prophylactic dose of azithromycin on Bifidobacterium infantis colonization in infants from the Mumta trial.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2025
    Trial
  11. Trial
  12. Trial
  13. Trial
  14. Trial
  15. Trial
  16. Trial
  17. Trial
  18. Trial
  19. Impact of Biannual Mass Azithromycin Treatment on Enteropathogen Carriage in Children <5 Years Old in Niger.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2022
    Trial
  20. Trial

28 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

T DoanFrancis I Proctor Foundation, University of California, San Francisco, CA, USA. Thuy.Doan@ucsf.edu.ORCID 0000-0003-2733-8370
A HinterwirthFrancis I Proctor Foundation, University of California, San Francisco, CA, USA.
L WordenFrancis I Proctor Foundation, University of California, San Francisco, CA, USA.
A M ArzikaThe Carter Center, Niamey, Niger.
R MalikiThe Carter Center, Niamey, Niger.
A AbdouMinistry of Public Health, Niamey, Niger.
S KaneThe Carter Center, Niamey, Niger.
L ZhongFrancis I Proctor Foundation, University of California, San Francisco, CA, USA.
M E CummingsFrancis I Proctor Foundation, University of California, San Francisco, CA, USA.
S SakarFrancis I Proctor Foundation, University of California, San Francisco, CA, USA.
C ChenFrancis I Proctor Foundation, University of California, San Francisco, CA, USA.
C CookFrancis I Proctor Foundation, University of California, San Francisco, CA, USA.
E LebasFrancis I Proctor Foundation, University of California, San Francisco, CA, USA.
E D ChowDepartment of Biochemistry and Biophysics, University of California, San Francisco, CA, USA.ORCID 0000-0001-8079-918X
I NachamkinPerelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
T C PorcoFrancis I Proctor Foundation, University of California, San Francisco, CA, USA.
J D KeenanFrancis I Proctor Foundation, University of California, San Francisco, CA, USA.ORCID 0000-0002-7118-1457
T M LietmanFrancis I Proctor Foundation, University of California, San Francisco, CA, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The MORDOR I trial

Indexed as

MetagenomicsAzithromycinCampylobacterCampylobacter InfectionsChildChild MortalityChild, PreschoolDrug Resistance, BacterialGastrointestinal MicrobiomeGene Expression Regulation, BacterialHumansMacrolidesMaleNigeriaSequence Analysis, RNAAzithromycinMacrolides

Identifiers

PMID31406349

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.