Evidence map›Paper›PMID 31406233›Full record

ArticleScientific reports2019

Dual-responsive (pH/temperature) Pluronic F-127 hydrogel drug delivery system for textile-based transdermal therapy.

Sudipta Chatterjee, Patrick Chi-Leung Hui, Chi-Wai Kan, Wenyi Wang

Abstract read
In one paragraph

Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 68 papers.

0numbers the graph read from it
0cells of the map it votes in
68citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

68 citing papers in PubMed.

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  13. Design Principles for Deployable Fibers Inspired by Hagfish Defense.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Article
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8 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Sudipta ChatterjeeInstitute of Textiles and Clothing, The Hong Kong Polytechnic University, Hung Hom, Hong Kong.
Patrick Chi-Leung HuiInstitute of Textiles and Clothing, The Hong Kong Polytechnic University, Hung Hom, Hong Kong. tchuip@polyu.edu.hk.
Chi-Wai KanInstitute of Textiles and Clothing, The Hong Kong Polytechnic University, Hung Hom, Hong Kong.
Wenyi WangInstitute of Textiles and Clothing, The Hong Kong Polytechnic University, Hung Hom, Hong Kong.ORCID http://orcid.org/0000-0001-6923-8613

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A dual-responsive hydrogel (pH/temperature) was developed from a thermos-responsive polymer, pluronic F-127 (PF127), and pH-responsive polymers, N,N,N-trimethyl chitosan (TMC) and polyethylene glycolated hyaluronic acid (PEG-HA). Gallic acid, the principal component of the traditional Chinese drug Cortex Moutan was loaded into the hydrogel (PF127/TMC/PEG-HA) for possible application in textile-based transdermal therapy as Cortex Moutan has been proven to be an effective drug for the treatment of atopic dermatitis (AD). TMC and PEG-HA were synthesized, characterized (

Indexed as

Transdermal PatchAdministration, CutaneousChemistry, PharmaceuticalChitosanDermatitis, AtopicDrug CarriersDrug CompoundingDrug LiberationDrugs, Chinese HerbalGallic AcidHumansHyaluronic AcidHydrogelsHydrogen-Ion ConcentrationPermeabilityPoloxamerChitosanDrug CarriersDrugs, Chinese HerbalGallic AcidHyaluronic AcidHydrogelsPoloxamer

Identifiers

PMID31406233
PMCPMC6690975

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.