ArticleScientific reports2019
Characterization and its implication of a novel taste receptor detecting nutrients in the honey bee, Apis mellifera.
Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 21 papers.
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21 citing papers in PubMed, 42 citations in OpenAlex.
- Integrated Ultrastructural and Transcriptomic Analysis of the Proboscis inAnimals : an open access journal from MDPI · 2026Article
- Diet Quality Shapes Metabolic and Immune Transcriptional Responses of Honey Bees Under Acute Heat Stress.Insects · 2026Article
- Never underestimate honeybees: Their exceptionally diverse adaptive strategies.Journal of advanced research · 2026Review
- Characterization of Umami Compounds and Volatile Profiles of Honeybee Brood Umami Powder Under Optimized Drying Conditions: Implications for Sensory Properties.Foods (Basel, Switzerland) · 2026Article
- Expanding the sensory horizon: chemosensory receptors beyond traditional olfactory and taste organs in insects.Science China. Life sciences · 2026Review
- Oxidation and allocation of nectar amino acids during butterfly flight.The Journal of experimental biology · 2026Article
- Analysis of antennal transcriptome and gustatory receptor genes in Apis cerana cerana collecting pollens from different nectar source plants.BMC genomics · 2025Article
- Expression analyses of chemosensory genes provide insights into evolution of gustatory receptor genes in the bumble bee Bombus impatiens.BMC genomics · 2025Article
- Gustatory sensitivity to amino acids in bumblebee mouthparts.Royal Society open science · 2025Article
- Do pollinators play a role in shaping the essential amino acids found in nectar?The New phytologist · 2025Article
- Pollen-Derived Fatty Acids and Amino Acids Mediate Variance in Pollinator Visitation.Journal of chemical ecology · 2025Article
- Molecular Functions and Physiological Roles of Gustatory Receptors of the SilkwormInternational journal of molecular sciences · 2024Review
- The Improving Effects of Probiotic-Added Pollen Substitute Diets on the Gut Microbiota and Individual Health of Honey Bee (Microorganisms · 2024Article
- Enhancing Honey Bee Health: Evaluating Pollen Substitute Diets in Field and Cage Experiments.Insects · 2024Article
- Remodeling of the ryanodine receptor isoform 1 channel regulates the sweet and umami taste perception ofFundamental research · 2023Article
- AmAtg2B-Mediated Lipophagy Regulates Lipolysis of Pupae inInternational journal of molecular sciences · 2023Article
- Toxic effects of detected pyrethroid pesticides on honeybee (Apis mellifera ligustica Spin and Apis cerana cerana Fabricius).Scientific reports · 2022Article
- Sweet solutions: nectar chemistry and quality.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2022Review
- Genome-Wide Identification and Analysis of Lipases in Fig Wasps (Chalcidoidea, Hymenoptera).Insects · 2022Article
- Sugar perception in honeybees.Frontiers in physiology · 2022Article
Corrections and comments
- Erratum issued
Authors and funding
5 authors at 1 institution in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Umami taste perception indicates the presence of amino acids, which are essential nutrients. Although the physiology of umami perception has been described in mammals, how insects detect amino acids remains unknown except in Drosophila melanogaster. We functionally characterized a gustatory receptor responding to L-amino acids in the western honey bee, Apis mellifera. Using a calcium-imaging assay and two-voltage clamp recording, we found that one of the honey bee's gustatory receptors, AmGr10, functions as a broadly tuned amino acid receptor responding to glutamate, aspartate, asparagine, arginine, lysine, and glutamine, but not to other sweet or bitter compounds. Furthermore, the sensitivity of AmGr10 to these L-amino acids was dramatically enhanced by purine ribonucleotides, like inosine-5'-monophosphate (IMP). Contact sensory hairs in the mouthpart of the honey bee responded strongly to glutamate and aspartate, which house gustatory receptor neurons expressing AmGr10. Interestingly, AmGr10 protein is highly conserved among hymenopterans but not other insects, implying unique functions in eusocial insects.
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