Evidence map›Paper›PMID 31405983›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2019

Human

Tae-Un Han, Jessica Root, Laura D Reyes, Elizabeth B Huchinson, Johann du Hoffmann, Wang-Sik Lee, Terra D Barnes, Dennis Drayna

Open access · bronzeAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
7.8field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 56 citations in OpenAlex.

  1. Review
  2. Article
  3. A stuttering-associatedbioRxiv : the preprint server for biology · 2025
    Article
  4. Review
  5. Article
  6. Article
  7. Review
  8. Review
  9. An active inference account of stuttering behavior.Frontiers in human neuroscience · 2025
    Article
  10. Article
  11. Article
  12. Article
  13. Stuttering as a spectrum disorder: A hypothesis.Current research in neurobiology · 2023
    Review
  14. Article
  15. Article
  16. Dopamine, vocalization, and astrocytes.Brain and language · 2021
    Article
  17. Article
  18. Evaluation of recurrentAdvanced genetics (Hoboken, N.J.) · 2021
    Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Tae-Un HanSection on Genetics of Communication Disorders, National Institute on Deafness and Other Communication Disorders, National Institutes of Health, Bethesda, MD 20892.
Jessica RootSection on Genetics of Communication Disorders, National Institute on Deafness and Other Communication Disorders, National Institutes of Health, Bethesda, MD 20892.
Laura D ReyesSection on Quantitative Medical Imaging, National Institute of Biomedical Imaging and Bioengineering, National Institutes of Health, Bethesda, MD 20892.
Elizabeth B HuchinsonSection on Quantitative Medical Imaging, National Institute of Biomedical Imaging and Bioengineering, National Institutes of Health, Bethesda, MD 20892.ORCID 0000-0002-3374-5469
Johann du HoffmannSection on Behavioral Neuroscience, Rodent Behavioral Core, National Institute of Mental Health, National Institutes of Health, Bethesda, MD 20892.
Wang-Sik LeeDepartment of Internal Medicine, Washington University School of Medicine in St. Louis, St. Louis, MO 63110.
Terra D BarnesDepartment of Neuroscience, Washington University School of Medicine in St. Louis, St. Louis, MO 63110.
Dennis DraynaSection on Genetics of Communication Disorders, National Institute on Deafness and Other Communication Disorders, National Institutes of Health, Bethesda, MD 20892; drayna@nidcd.nih.gov.ORCID 0000-0002-1730-4532
National Institutes of Health · USWashington University in St. Louis · US

Funding

Genetic Studies of Human Communications DisordersZIADC000046 · NIDCD · NATIONAL INSTITUTE ON DEAFNESS AND OTHER COMMUNICATION DISORDERS · PI DRAYNA, DENNIS · 2009 to 2019
$21.1M
Rodent Behavioral Core: The Analysis of BehaviorZICMH002952 · NIMH · NATIONAL INSTITUTE OF MENTAL HEALTH · PI CHUDASAMA, YOGITA · 2016 to 2025
$7.5M
6 · The paper itself

Abstract

Stuttering is a common neurodevelopmental disorder that has been associated with mutations in genes involved in intracellular trafficking. However, the cellular mechanisms leading to stuttering remain unknown. Engineering a mutation in

Indexed as

MutationVocalization, AnimalAnimalsAstrocytesCell CountCorpus CallosumDisease Models, AnimalHumansMaleMiceMice, TransgenicPhenotypePhosphoric Diester HydrolasesStutteringTransferases (Other Substituted Phosphate Groups)GNPTAB protein, humanPhosphoric Diester HydrolasesTransferases (Other Substituted Phosphate Groups)astrocytesCre-driversmouse vocalizationstutteringwhite matter

Identifiers

PMID31405983
PMCPMC6717282
OpenAlexW2967025747

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.