Evidence map›Paper›PMID 31405957›Full record

ArticleInfection and immunity2019

Proximity Labeling To Map Host-Pathogen Interactions at the Membrane of a Bacterium-Containing Vacuole in Chlamydia trachomatis-Infected Human Cells.

Macy G Olson, Ray E Widner, Lisa M Jorgenson, Alyssa Lawrence, Dragana Lagundzin, Nicholas T Woods, Scot P Ouellette, Elizabeth A Rucks

Open access · hybridAbstract read
In one paragraph

Article in Infection and immunity, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed, 1 pooled it
3.1field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 1 synthesis or guideline pooled it, 42 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Review
  5. Review
  6. Article
  7. Article
  8. Review
  9. Mapping of the hSOX10 protein interactome in human melanoma.bioRxiv : the preprint server for biology · 2025
    Article
  10. ThebioRxiv : the preprint server for biology · 2025
    Article
  11. Review
  12. Protease shaving ofMicrobiology spectrum · 2025
    Article
  13. Article
  14. mSphere · 2024
    Article
  15. Article
  16. Review
  17. Protease shaving ofbioRxiv : the preprint server for biology · 2024
    Article
  18. Article
  19. Identification of potential nucleomodulins ofFrontiers in microbiology · 2024
    Article
  20. Type III Secretion inMicrobiology and molecular biology reviews : MMBR · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Macy G OlsonDepartment of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, Nebraska, USA.ORCID 0000-0001-6027-8061
Ray E WidnerDepartment of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, Nebraska, USA.
Lisa M JorgensonDepartment of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, Nebraska, USA.
Alyssa LawrenceDepartment of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, Nebraska, USA.
Dragana LagundzinThe Mass Spectrometry and Proteomics Core Facility, University of Nebraska Medical Center, Omaha, Nebraska, USA.
Nicholas T WoodsEppley Institute for Research in Cancer and Allied Diseases, Fred & Pamela Buffett Cancer Center, University of Nebraska Medical Center, Omaha, Nebraska, USA.
Scot P OuelletteDepartment of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, Nebraska, USA scot.ouellette@unmc.edu lisa.rucks@unmc.edu.ORCID 0000-0002-3721-6839
Elizabeth A RucksDepartment of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, Nebraska, USA scot.ouellette@unmc.edu lisa.rucks@unmc.edu.ORCID 0000-0002-0536-7691
University of Nebraska Medical Center · US

Funding

UNMC Structural Biology CoreP20GM103427 · NIGMS · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI Heather Colleen Jensen-Smith · 2012 to 2026
$59.2M
UNMC/EPPLEY CANCER CENTER SUPPORT GRANTP30CA036727 · NCI · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI Apar Kishor Ganti · 1985 to 2026
$55.0M
Target Validation CoreP20GM121316 · NIGMS · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI Robert E. Lewis · 2018 to 2026
$23.5M
Research Pilot Project ProgramP30GM106397 · NIGMS · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI JOHNSON, KEITH R · 2013 to 2017
$4.9M
SNAREs and the biogenesis of the chlamydial inclusion membraneR01AI114670 · NIAID · UNIVERSITY OF SOUTH DAKOTA · PI RUCKS, ELIZABETH ANN · 2016 to 2020
$1.8M
Polarized Chlamydial Cell Division in the Absence of FtsZR35GM124798 · NIGMS · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI OUELLETTE, SCOT P · 2017 to 2021
$1.8M
Tansmission Electron Microscope for Analytical MicoscopyS10RR024650 · NCRR · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI TODD, GORDON LIVINGSTON · 2009 to 2009
$377k
NCI NIH HHS P30 CA036727NCRR NIH HHS S10 RR024650NIAID NIH HHS R01 AI114670NIGMS NIH HHS P20 GM103427NIGMS NIH HHS P20 GM121316NIGMS NIH HHS P30 GM106397NIGMS NIH HHS R35 GM124798
6 · The paper itself

Abstract

Many intracellular bacteria, including the obligate intracellular pathogen

Indexed as

Bacterial ProteinsBiotinylationChlamydia trachomatisGene Expression Regulation, BacterialHeLa CellsHumansMass SpectrometryMembrane ProteinsRecombinant ProteinsStreptavidinBacterial ProteinsMembrane ProteinsRecombinant ProteinsStreptavidinAPEX2Chlamydia trachomatishost-pathogen interactionsinclusion membraneInc proteinsLRRF1proximity labeling

Identifiers

PMID31405957
PMCPMC6803327
OpenAlexW2968532471

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.