ArticleAntimicrobial agents and chemotherapy2019
Isavuconazole Diffusion in Infected Human Brain.
Article in Antimicrobial agents and chemotherapy, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
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Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Aspergillosis of central nervous system in patients with leukemia and stem cell transplantation: a systematic review of case reports.Annals of clinical microbiology and antimicrobials · 2021Pooled it
- Cerebral Aspergillosis: Diagnostic Challenges, Therapeutic Strategies, and Future Research.CNS drugs · 2026Review
- Antifungal drug penetration in soft tissue abscesses: a comparative analysis.The Journal of antimicrobial chemotherapy · 2024Article
- Pharmacokinetics of isavuconazole at different target sites in healthy volunteers after single and multiple intravenous infusions.The Journal of antimicrobial chemotherapy · 2024Article
- Bronchopulmonary penetration of isavuconazole in lung transplant recipients.Antimicrobial agents and chemotherapy · 2023Article
- Successful Multimodal Therapy with Intracerebral Liposomal Amphotericin B and Systemic High-Dose Isavuconazole in Proven Disseminated Aspergillosis.Journal of fungi (Basel, Switzerland) · 2023Article
- Management of Histoplasmosis by Infectious Disease Physicians.Open forum infectious diseases · 2022Article
- Isavuconazole for COVID-19-Associated Invasive Mold Infections.Journal of fungi (Basel, Switzerland) · 2022Review
- Isavuconazole Treatment of Spinal Cord Invasive Aspergillosis Guided by Cerebrospinal Fluid (1,3)-β-d-Glucan Levels in a Patient with Low Interferon-Gamma and Ulcerative Colitis.Journal of fungi (Basel, Switzerland) · 2022Article
- Successful Treatment of Cryptococcal Meningitis and Cryptococcoma with Isavuconazole in a Patient Living with HIV.Journal of fungi (Basel, Switzerland) · 2021Article
- Penetration of Isavuconazole in Ascites Fluid of Critically Ill Patients.Journal of fungi (Basel, Switzerland) · 2021Article
- Isolated Cerebral Mucormycosis in Immunocompetent Adults who Inject Drugs: Case Reports and Systematic Review of the Literature.Open forum infectious diseases · 2020Article
- Isavuconazole-Animal Data and Clinical Data.Journal of fungi (Basel, Switzerland) · 2020Review
- Isavuconazole Treatment in a Mixed Patient Cohort with Invasive Fungal Infections: Outcome, Tolerability and Clinical Implications of Isavuconazole Plasma Concentrations.Journal of fungi (Basel, Switzerland) · 2020Article
- Isavuconazole for the treatment of patients with invasive fungal diseases involving the central nervous system.Medical mycology · 2020Article
- Azole-resistant Aspergillus and Echinocandin-resistant Candida - What are the treatment options?Current fungal infection reports · 2020Article
- Applying Pharmacogenomics to Antifungal Selection and Dosing: Are We There Yet?Current fungal infection reports · 2020Article
- Isavuconazole Therapy of Disseminated and EncephalicMediterranean journal of hematology and infectious diseases · 2020Article
- Successful use of isavuconazole as secondary prophylaxis of cryptococcal meningitis in a person living with HIV and AIDS: a case report.Therapeutic advances in infectious diseaseArticle
Corrections and comments
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Authors and funding
13 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We report the cases of a 39-year-old woman with chronic lymphocytic leukemia and a 21-year-old man with chronic granulomatous disease treated for cerebral aspergillosis. The patients required radical surgery for infection progression despite adequate isavuconazole plasma concentration or neurological complication. We thus decided to measure the brain isavuconazole concentration. These results suggest that the concentrations of isavuconazole obtained in the infected brain tissue clearly differ from those obtained in the normal brain tissue and the cerebrospinal fluid.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.