Evidence map›Paper›PMID 31405724›Full record

SynthesisAcademic radiology2019

Automated Segmentation of Tissues Using CT and MRI: A Systematic Review.

Leon Lenchik, Laura Heacock, Ashley A Weaver, Robert D Boutin, Tessa S Cook, Jason Itri, Christopher G Filippi, Rao P Gullapalli, James Lee, Marianna Zagurovskaya and 4 more

Registry-linked trialAbstract readSystematic Review
In one paragraph

Synthesis in Academic radiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06108310 (ATTRACT - ArTificial inTelligence-based RAdiogenomics in Colon Tumors), which is not on this map. Cited by 69 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
69citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06108310 unknown statusnot on this mapstarted 2021, after this paper: background citation

ATTRACT - ArTificial inTelligence-based RAdiogenomics in Colon Tumors

TypeobservationalSponsorUniversity of Roma La SapienzaRan2021 to 2025Enrolled500ConditionsColon Cancer Stage II, Colon Cancer Stage III
3 · Its place in the literature

Who cites it

69 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Automated Muscle Measurement on Chest CT Predicts All-Cause Mortality in Older Adults From the National Lung Screening Trial.The journals of gerontology. Series A, Biological sciences and medical sciences · 2021
    Trial
  5. Review
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  11. Review
  12. Automated vs. manual segmentation for small renal mass imaging.Canadian Urological Association journal = Journal de l'Association des urologues du Canada · 2026
    Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
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  20. Article

9 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Leon LenchikDepartment of Radiology, Wake Forest School of Medicine, Medical Center Boulevard, Winston-Salem, NC 27157. Electronic address: llenchik@wakehealth.edu.
Laura HeacockDepartment of Radiology, NYU Langone, New York, New York.
Ashley A WeaverDepartment of Biomedical Engineering, Wake Forest School of Medicine, Winston-Salem, North Carolina.
Robert D BoutinDepartment of Radiology, University of California Davis School of Medicine, Sacramento, California.
Tessa S CookDepartment of Radiology, University of Pennsylvania, Philadelphia Pennsylvania.
Jason ItriDepartment of Radiology, Wake Forest School of Medicine, Medical Center Boulevard, Winston-Salem, NC 27157.
Christopher G FilippiDepartment of Radiology, Donald and Barbara School of Medicine at Hofstra/Northwell, Lenox Hill Hospital, NY, New York.
Rao P GullapalliDepartment of Radiology, University of Maryland School of Medicine, Baltimore, Maryland.
James LeeDepartment of Radiology, University of Kentucky, Lexington, Kentucky.
Marianna ZagurovskayaDepartment of Radiology, University of Kentucky, Lexington, Kentucky.
Tara RetsonDepartment of Radiology, University of California San Diego, San Diego, California.
Kendra GodwinMedical Library, Memorial Sloan Kettering Cancer Center, New York, New York.
Joey NicholsonNYU Health Sciences Library, NYU School of Medicine, NYU Langone Health, New York, New York.
Ponnada A NarayanaDepartment of Diagnostic and Interventional Imaging, McGovern Medical School, University of Texas Health Science Center at Houston, Houston, Texas.

Funding

Wake Forest Claude D. Pepper OAIC - RenewalP30AG021332 · NIA · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI Denise Kathryn Houston · 2002 to 2026
$36.4M
Effect of protein supplementation during weight loss on older adult bone healthK25AG058804 · NIA · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI WEAVER, ASHLEY · 2019 to 2023
$672k
NIA NIH HHS K25 AG058804NIA NIH HHS P30 AG021332
6 · The paper itself

Abstract

RATIONALE AND

objectivesThe automated segmentation of organs and tissues throughout the body using computed tomography and magnetic resonance imaging has been rapidly increasing. Research into many medical conditions has benefited greatly from these approaches by allowing the development of more rapid and reproducible quantitative imaging markers. These markers have been used to help diagnose disease, determine prognosis, select patients for therapy, and follow responses to therapy. Because some of these tools are now transitioning from research environments to clinical practice, it is important for radiologists to become familiar with various methods used for automated segmentation. MATERIALS AND

methodsThe Radiology Research Alliance of the Association of University Radiologists convened an Automated Segmentation Task Force to conduct a systematic review of the peer-reviewed literature on this topic.

resultsThe systematic review presented here includes 408 studies and discusses various approaches to automated segmentation using computed tomography and magnetic resonance imaging for neurologic, thoracic, abdominal, musculoskeletal, and breast imaging applications.

conclusionThese insights should help prepare radiologists to better evaluate automated segmentation tools and apply them not only to research, but eventually to clinical practice.

Indexed as

AlgorithmsAutomationHumansMagnetic Resonance ImagingTomography, X-Ray ComputedCTMachine learningMRIQuantitative imagingSegmentation

Identifiers

PMID31405724
PMCPMC6878163

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.