Evidence map›Paper›PMID 31405719›Full record

ArticleAnnals of epidemiology2019

Identifying high-risk areas for nonfatal opioid overdose: a spatial case-control study using EMS run data.

Jeffrey Pesarsick, Melody Gwilliam, Olayemi Adeniran, Toni Rudisill, Gordon Smith, Brian Hendricks

Abstract read
In one paragraph

Article in Annals of epidemiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jeffrey PesarsickDepartment of Epidemiology, West Virginia University, Morgantown.
Melody GwilliamDepartment of Epidemiology, West Virginia University, Morgantown.
Olayemi AdeniranDepartment of Epidemiology, West Virginia University, Morgantown.
Toni RudisillDepartment of Epidemiology, West Virginia University, Morgantown.
Gordon SmithDepartment of Epidemiology, West Virginia University, Morgantown.
Brian HendricksDepartment of Epidemiology, West Virginia University, Morgantown. Electronic address: bmhendricks@hsc.wvu.edu.

Funding

West Virginia IDEA-CTRU54GM104942 · NIGMS · WEST VIRGINIA UNIVERSITY · PI JUDITH FEINBERG · 2012 to 2026
$81.0M
Rural West Virginia Responds to Opioid Injection Epidemics: From Data to ActionUG3DA044825 · NIDA · WEST VIRGINIA UNIVERSITY · PI FEINBERG, JUDITH, SMITH, GORDON STEPHEN · 2017 to 2018
$1.0M
Drugs and Driving: Developing a Sentinel Drug_FARS for ResearchR21DA040187 · NIDA · WEST VIRGINIA UNIVERSITY · PI SMITH, GORDON STEPHEN · 2016 to 2017
$360k
NIDA NIH HHS R21 DA040187NIDA NIH HHS UG3 DA044825NIGMS NIH HHS U54 GM104942
6 · The paper itself

Abstract

purposeThe objective of our study was to incorporate stricter probable nonfatal opioid overdose case criteria, and advanced epidemiologic approaches to more reliably detect local clustering in nonfatal opioid overdose activity in EMS runs data.

methodsData were obtained using emsCharts for our study area in southwestern Pennsylvania from 2007 to 2018. Cases were identified as emergency medical service (EMS) responses where naloxone was administered, and improvement was noted in patient records between initial and final Glasgow Coma Score. A subsample of all-cause EMS responses sites were used as controls and exact matched to cases on sex and 10-year-age category. Clustering was assessed using difference in Ripley's K function for cases and controls and Kulldorff scan statistics.

resultsDifference in K functions indicated no significant difference in probable nonfatal overdose EMS runs across the study area compared to all-cause EMS runs. However, scan statistics did identify significant local clustering of probable nonfatal overdose EMS runs (maximum likelihood = 16.40, P = 0.0003).

conclusionsResults highlight relevance of EMS data to detect community-level overdose activity and promote reliable use through stricter case definition criteria and advanced methodological approaches. Techniques examined have the potential to improve targeted delivery of neighborhood-level public health response activities using a near real-time data source.

Indexed as

Analgesics, OpioidCase-Control StudiesCluster AnalysisDrug OverdoseEmergency Medical ServicesGeographic Information SystemsHumansNaloxoneNarcotic AntagonistsOpioid-Related DisordersPennsylvaniaSpatial AnalysisAnalgesics, OpioidNaloxoneNarcotic AntagonistsCluster analysisEMS runsNonfatal overdose

Identifiers

PMID31405719
PMCPMC6733038

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.