ArticleIntegrative cancer therapies
Literature Review of Traditional Chinese Medicine Herbs-Induced Liver Injury From an Oncological Perspective With RUCAM.
Article in Integrative cancer therapies. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed.
- Acute liver failure caused by alkaloids from traditional Chinese medicine: A case report.World journal of hepatology · 2025Article
- NLRP3 Inflammasome Activation Is Involved in Geniposide-Induced Hepatotoxicity.Mediators of inflammation · 2025Article
- Impact of Traditional Chinese Medicine Antioxidants on Oxidative Stress and Drug-Induced Liver Injury: A Review.Medical science monitor : international medical journal of experimental and clinical research · 2024Review
- Developing implementation strategies for promoting integrative oncology outpatient service delivery and utilisation: a qualitative study in Hong Kong.Frontiers in public health · 2024Article
- Baseline lymphocyte and cholinesterase levels may be the predictors of chronic herbal drug-induced liver injury.Frontiers in pharmacology · 2022Article
- Investigation ofFrontiers in microbiology · 2022Article
- Metabolic Toxification of 1,2-Unsaturated Pyrrolizidine Alkaloids Causes Human Hepatic Sinusoidal Obstruction Syndrome: The Update.International journal of molecular sciences · 2021Review
- Herb-induced liver injury: Systematic review and meta-analysis.World journal of clinical cases · 2021Article
- Case series and review of Ayurvedic medication induced liver injury.BMC complementary medicine and therapies · 2021Review
- Herb-induced liver injury (HILI) with 12,068 worldwide cases published with causality assessments by Roussel Uclaf Causality Assessment Method (RUCAM): an overview.Translational gastroenterology and hepatology · 2021Review
- Herb-induced Liver Injury in Asia and Current Role of RUCAM for Causality Assessment in 11,160 Published Cases.Journal of clinical and translational hepatology · 2020Review
- Screening of the Hepatotoxic Components inMolecules (Basel, Switzerland) · 2019Article
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Traditional Chinese medicine (TCM) herbs are commonly regarded to be safe with minimal toxicities in Chinese communities. Cancer patients who are receiving Western oncology therapy often concurrently take TCM herbs for anticancer and symptom relief purposes. We performed a literature review for current evidence on TCM herb-induced liver injury from an oncological perspective. A literature search on PubMed was performed to identify publications regarding TCM herbs and concoctions with hepatoprotective or hepatotoxic properties. Lists of commonly used herbs and their causality levels were compiled. In view of the wide range of evidence available, cases assessed by the well-established RUCAM (Roussel Uclaf Causality Assessment Method) algorithm were categorized as the highest level of evidence. More than one case of TCM herb-induced liver injury was confirmed by RUCAM in the following herbs and concoctions: Lu Cha (
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