Evidence map›Paper›PMID 31405214›Full record

ArticleMolecules (Basel, Switzerland)2019

Diselenides and Benzisoselenazolones as Antiproliferative Agents and Glutathione-S-Transferase Inhibitors.

Dorota Krasowska, Nunzio Iraci, Claudio Santi, Józef Drabowicz, Marcin Cieslak, Julia Kaźmierczak-Barańska, Martina Palomba, Karolina Królewska-Golińska, Jakub Magiera, Luca Sancineto

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
3.9field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 47 citations in OpenAlex.

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  14. Selenium Compounds as Novel Potential Anticancer Agents.International journal of molecular sciences · 2021
    Review
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 2 countries.

Dorota KrasowskaDivision of Organic Chemistry, Centre of Molecular and Macromolecular Studies, Polish Academy of Science, Sienkiewicza, 112, 90-363 Lodz, Poland.ORCID 0000-0002-2361-6401
Nunzio IraciDepartment of Pharmacy, University of Salerno, Via G. Paolo II 132, 84084 Fisciano, Salerno, Italy.ORCID 0000-0002-1359-8684
Claudio SantiDepartment of Pharmaceutical Sciences, University of Perugia, Via del Liceo 1, 06123 Perugia, Italy.ORCID 0000-0002-7698-8970
Józef DrabowiczDivision of Organic Chemistry, Centre of Molecular and Macromolecular Studies, Polish Academy of Science, Sienkiewicza, 112, 90-363 Lodz, Poland.
Marcin CieslakDivision of Bioorganic Chemistry, Centre of Molecular and Macromolecular Studies, Polish Academy of Science, Sienkiewicza, 112, 90-363 Lodz, Poland.ORCID 0000-0002-9628-214X
Julia Kaźmierczak-BarańskaDivision of Bioorganic Chemistry, Centre of Molecular and Macromolecular Studies, Polish Academy of Science, Sienkiewicza, 112, 90-363 Lodz, Poland.
Martina PalombaDepartment of Pharmaceutical Sciences, University of Perugia, Via del Liceo 1, 06123 Perugia, Italy.
Karolina Królewska-GolińskaDivision of Bioorganic Chemistry, Centre of Molecular and Macromolecular Studies, Polish Academy of Science, Sienkiewicza, 112, 90-363 Lodz, Poland.
Jakub MagieraDivision of Bioorganic Chemistry, Centre of Molecular and Macromolecular Studies, Polish Academy of Science, Sienkiewicza, 112, 90-363 Lodz, Poland.
Luca SancinetoDivision of Organic Chemistry, Centre of Molecular and Macromolecular Studies, Polish Academy of Science, Sienkiewicza, 112, 90-363 Lodz, Poland. sancineto.luca@gmail.com.
Centrum Badań Molekularnych i Makromolekularnych Polskiej Akademii Nauk · PLUniversity of Perugia · ITJan Długosz University · PLUniversity of Salerno · IT

Funding

Narodowe Centrum Nauki 2016/21/P/ST5/03512
6 · The paper itself

Abstract

A series of variously functionalized selenium-containing compounds were purposely synthesized and evaluated against a panel of cancer cell lines. Most of the compounds showed an interesting cytotoxicity profile with compound

Indexed as

Antineoplastic AgentsEnzyme InhibitorsOrganoselenium CompoundsSelenium CompoundsCell ProliferationCytotoxinsGlutathione TransferaseHeLa CellsHumansHuman Umbilical Vein Endothelial CellsK562 CellsMCF-7 CellsNeoplasm ProteinsAntineoplastic AgentsCytotoxinsEnzyme InhibitorsGlutathione TransferaseNeoplasm ProteinsOrganoselenium CompoundsSelenium Compoundsbenzisoselenazolonebreast cancerdiselenideglutathione S-transferase

Identifiers

PMID31405214
PMCPMC6721112
OpenAlexW2967687900

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.