Evidence map›Paper›PMID 31405173›Full record

ReviewMarine drugs2019

Marine Collagen as A Promising Biomaterial for Biomedical Applications.

Ye-Seon Lim, Ye-Jin Ok, Seon-Yeong Hwang, Jong-Young Kwak, Sik Yoon

Open access · goldAbstract readReview
In one paragraph

Review in Marine drugs, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 118 papers.

0numbers the graph read from it
0cells of the map it votes in
118citing papers in PubMed
11.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

118 citing papers in PubMed, 313 citations in OpenAlex.

  1. Article
  2. Review
  3. The Digestive System of the Greater Weever (International journal of molecular sciences · 2026
    Article
  4. Article
  5. Review
  6. Article
  7. Review
  8. Therapeutic potential of fish collagen hydrolysates in osteoporosis prevention: a narrative review based on cellular, molecular, and clinical evidence.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2026
    Review
  9. Unraveling the Potential ofBiomacromolecules · 2026
    Article
  10. Article
  11. Collagen from Marine Sources for Potential Application in Wound Treatment.Progress in molecular and subcellular biology · 2026
    Review
  12. Article
  13. Review
  14. Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Review
  20. Article

58 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Ye-Seon LimDepartment of Anatomy, School of Medicine, Pusan National University, Yangsan 50612, Korea.
Ye-Jin OkDepartment of Anatomy, School of Medicine, Pusan National University, Yangsan 50612, Korea.
Seon-Yeong HwangDepartment of Anatomy, School of Medicine, Pusan National University, Yangsan 50612, Korea.
Jong-Young KwakDepartment of Pharmacology, School of Medicine, Ajou University, Suwon 16499, Korea.
Sik YoonDepartment of Anatomy, School of Medicine, Pusan National University, Yangsan 50612, Korea. sikyoon@pusan.ac.kr.ORCID 0000-0002-6449-0761
Pusan National University · KRAjou University · KR

Funding

The National Research Foundation of Korea(NRF) grant funded by the Korea government(MSIT) No. 2017R1A2B4012354
6 · The paper itself

Abstract

This review focuses on the expanding role of marine collagen (MC)-based scaffolds for biomedical applications. A scaffold-a three-dimensional (3D) structure fabricated from biomaterials-is a key supporting element for cell attachment, growth, and maintenance in 3D cell culture and tissue engineering. The mechanical and biological properties of the scaffolds influence cell morphology, behavior, and function. MC, collagen derived from marine organisms, offers advantages over mammalian collagen due to its biocompatibility, biodegradability, easy extractability, water solubility, safety, low immunogenicity, and low production costs. In recent years, the use of MC as an increasingly valuable scaffold biomaterial has drawn considerable attention from biomedical researchers. The characteristics, isolation, physical, and biochemical properties of MC are discussed as an understanding of MC in optimizing the subsequent modification and the chemistries behind important tissue engineering applications. The latest technologies behind scaffold processing are assessed and the biomedical applications of MC and MC-based scaffolds, including tissue engineering and regeneration, wound dressing, drug delivery, and therapeutic approach for diseases, especially those associated with metabolic disturbances such as obesity and diabetes, are discussed. Despite all the challenges, MC holds great promise as a biomaterial for developing medical products and therapeutics.

Indexed as

AnimalsAquatic OrganismsBiocompatible MaterialsCollagenHumansTissue EngineeringTissue ScaffoldsBiocompatible MaterialsCollagen3D cell culturemarine collagenscaffoldstissue engineeringtissue regeneration

Identifiers

PMID31405173
PMCPMC6723527
OpenAlexW2967753885

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.