Evidence map›Paper›PMID 31404988›Full record

ReviewCells2019

The Prospect and Challenges to the Flow of Liquid Biopsy in Africa.

Dada Oluwaseyi Temilola, Martha Wium, Tangbadioa Herve Coulidiati, Henry Ademola Adeola, Giuseppina Maria Carbone, Carlo Vittorio Catapano, Luiz Fernando Zerbini

Open access · goldAbstract readReview
In one paragraph

Review in Cells, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 38 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Liquid Biopsy in the Clinical Management of Cancers.International journal of molecular sciences · 2024
    Review
  6. Review
  7. Article
  8. Article
  9. Review
  10. Review
  11. The integrated comprehension of lncRNA HOXA-AS3 implication on human diseases.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2022
    Review
  12. Fighting Cancer around the World: A Framework for Action.Healthcare (Basel, Switzerland) · 2022
    Article
  13. Review
  14. Article
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 3 countries.

Dada Oluwaseyi TemilolaInternational Centre for Genetic Engineering and Biotechnology (ICGEB), Cape Town 7925, South Africa.
Martha WiumInternational Centre for Genetic Engineering and Biotechnology (ICGEB), Cape Town 7925, South Africa.ORCID 0000-0003-0527-1750
Tangbadioa Herve CoulidiatiInternational Centre for Genetic Engineering and Biotechnology (ICGEB), Cape Town 7925, South Africa.ORCID 0000-0003-0658-496X
Henry Ademola AdeolaDivision of Dermatology, Department of Medicine, Faculty of Health Sciences and Groote Schuur Hospital, University of Cape Town, Cape Town 7925, South Africa.
Giuseppina Maria CarboneInstitute of Oncology Research, Università della Svizzera Italiana, Via Vincenzo Vela 6, CH-6500 Bellinzona, Switzerland.
Carlo Vittorio CatapanoInstitute of Oncology Research, Università della Svizzera Italiana, Via Vincenzo Vela 6, CH-6500 Bellinzona, Switzerland.ORCID 0000-0002-7079-557X
Luiz Fernando ZerbiniInternational Centre for Genetic Engineering and Biotechnology (ICGEB), Cape Town 7925, South Africa. luiz.zerbini@icgeb.org.ORCID 0000-0003-0736-9508
International Centre for Genetic Engineering and Biotechnology · ZAInstitute of Oncology Research · CHUniversity of Cape Town · ZA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Liquid biopsy technologies have the potential to transform cancer patient management as it offers non-invasive diagnosis and real-time monitoring of disease progression and treatment responses. The use of liquid biopsy for non-invasive cancer diagnosis can have pivotal importance for the African continent where access to medical infrastructures is limited, as it eliminates the need for surgical biopsies. To apply liquid biopsy technologies in the African setting, the influence of environmental and population genetic factors must be known. In this review, we discuss the use of circulating tumor cells, cell-free nucleic acids, extracellular vesicles, protein, and other biomolecules in liquid biopsy technology for cancer management with special focus on African studies. We discussed the prospect, barriers, and other aspects that pose challenges to the use of liquid biopsy in the African continent.

Indexed as

Liquid BiopsyAfricaBiomarkers, TumorHumansNeoplasmsNeoplastic Cells, CirculatingBiomarkers, TumorAfricacancercell-free DNAcirculating RNAcirculating tumor cellliquid biopsynon-invasive

Identifiers

PMID31404988
PMCPMC6721679
OpenAlexW2967314854

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.