Evidence map›Paper›PMID 31404979›Full record

ReviewJournal of fungi (Basel, Switzerland)2019

Histoplasmosis and Tuberculosis Co-Occurrence in People with Advanced HIV.

Diego H Caceres, Audrey Valdes

Open access · goldAbstract readReview
In one paragraph

Review in Journal of fungi (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed, 1 pooled it
4.5field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 1 synthesis or guideline pooled it, 69 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. AIDS research and human retroviruses · 2025
    Article
  4. Observational
  5. Article
  6. Review
  7. Review
  8. Article
  9. Article
  10. Observational
  11. Article
  12. Disseminated histoplasmosis with skin manifestations in advanced HIV: Case report.Revista medica del Instituto Mexicano del Seguro Social · 2024
    Article
  13. Design of a Multi-Epitope Vaccine againstJournal of fungi (Basel, Switzerland) · 2024
    Article
  14. Article
  15. Article
  16. Article
  17. Prevalence ofJournal of fungi (Basel, Switzerland) · 2023
    Article
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 3 countries.

Diego H CaceresMycotic Diseases Branch, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA. diegocaceres84@gmail.com.ORCID 0000-0001-8749-9809
Audrey ValdesService de Maladies Infectieuses et Tropicales, Centre Hospitalier de Cayenne, 97306 Cayenne, French Guiana. xju7@cdc.gov.
Centers for Disease Control and Prevention · USCentre Hospitalier Andrée Rosemon · GF

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Distinguishing between histoplasmosis, tuberculosis (TB), and co-occurrence of disease is a frequent dilemma for clinical staff treating people with advanced Human Immunodeficiency Virus (HIV) infection. This problem is most frequently observed in clinical settings in countries where both diseases are endemic. It is also a challenge outside these endemic countries in HIV clinics that take care of patients coming from countries with endemic histoplasmosis and TB. The gold standard for diagnosis of both of these diseases is based on conventional laboratory tests (culture, histopathology and special stains). These tests have several limitations, such as lack of laboratory infrastructure for handling isolates (biosafety level 3), shortage of laboratory staff who have appropriate training and experience, variable analytical performance of tests and long turn-around time. Recently, novel rapid assays for the diagnosis of histoplasmosis and TB became available. However, this technology is not yet widely used. Mortality in immunocompromised patients, such as people with advanced HIV, is directly linked with the ability to rapidly diagnose opportunistic diseases. The aim of this review is to synthesize the main aspects of epidemiology, clinical characteristics, diagnosis and treatment of histoplasmosis/TB co-occurrence in people with advanced HIV.

Indexed as

AIDSco-occurrencediagnosisepidemiologyhistoplasmosisHIVtreatmenttuberculosis

Identifiers

PMID31404979
PMCPMC6787747
OpenAlexW2967060157

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.