ArticlePediatric research2020
NeoDoppler: New ultrasound technology for continous cerebral circulation monitoring in neonates.
Article in Pediatric research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
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Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it, 37 citations in OpenAlex.
- Occurrence and Time of Onset of Intraventricular Hemorrhage in Preterm Neonates: A Systematic Review and Meta-Analysis of Individual Patient Data.JAMA pediatrics · 2025Pooled it
- Preoperative Hemodynamics and Brain Injury in Transposition of the Great Arteries.JACC. Advances · 2026Article
- Cerebral blood flow dynamics during cardiac surgery in infants.Pediatric research · 2025Article
- Noninvasive optical monitoring of cerebral hemodynamics in a preclinical model of neonatal intraventricular hemorrhage.Frontiers in pediatrics · 2025Article
- Quantification of brain-wide vascular resistivity via ultrafast Doppler in human neonates helps early detection of white matter injury.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2024Article
- Neurosonography: Shaping the future of neuroprotection strategies in extremely preterm infants.Heliyon · 2024Review
- Instant Detection of Cerebral Blood Flow Changes in Infants with Congenital Heart Disease during Transcatheter Interventions.Journal of clinical medicine · 2024Article
- Continuous cerebral blood flow monitoring: What should we do with these extra numbers?BJA open · 2023Article
- Hands-free continuous carotid Doppler ultrasound for detection of the pulse during cardiac arrest in a porcine model.Resuscitation plus · 2023Article
- Article
- Transfontanelle photoacoustic imaging: ultrasound transducer selection analysis.Biomedical optics express · 2022Article
- Low frequency cerebral arterial and venous flow oscillations in healthy neonates measured by NeoDoppler.Frontiers in pediatrics · 2022Article
- Effects of tilt on cerebral hemodynamics measured by NeoDoppler in healthy neonates.Pediatric research · 2021Article
- Perspectives from the Society for Pediatric Research. Neonatal encephalopathy clinical trials: developing the future.Pediatric research · 2021Review
- Feasibility of Doppler Ultrasound for Cortical Cerebral Blood Flow Velocity Monitoring During Major Non-cardiac Surgery of Newborns.Frontiers in pediatrics · 2021Article
- Chest Compression in Neonatal Cardiac Arrest: Cerebral Blood Flow Measurements in Experimental Models.Healthcare (Basel, Switzerland) · 2020Review
- Femoral Nailing in a Porcine Model Causes Bone Marrow Emboli in the Lungs and Systemic Emboli in the Heart and Brain.JB & JS open accessArticle
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThere is a strong need for continuous cerebral circulation monitoring in neonatal care, since suboptimal cerebral blood flow may lead to brain injuries in preterm infants and other critically ill neonates. NeoDoppler is a novel ultrasound system, which can be gently fixed to the anterior fontanel and measure cerebral blood flow velocity continuously in different depths of the brain simultaneously. We aimed to study the feasibility, accuracy, and potential clinical applications of NeoDoppler in preterm infants and sick neonates.
methodTwenty-five infants born at different gestational ages with a variety of diagnoses on admission were included. The probe was placed over the anterior fontanel, and blood flow velocity data were continuously recorded. To validate NeoDoppler, we compared the measurements with conventional ultrasound; agreement was assessed using Bland-Altman plots.
resultsNeoDoppler can provide accurate and continuous data on cerebral blood flow velocity in several depths simultaneously. Limits of agreement between the measurements obtained with the two methods were acceptable.
conclusionBy monitoring the cerebral circulation continuously, increased knowledge of cerebral hemodynamics in preterm infants and sick neonates may be acquired. Improved monitoring of these vulnerable brains during a very sensitive period of brain development may contribute toward preventing brain injuries.
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Registered trials
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