Evidence map›Paper›PMID 31404555›Full record

ReviewToxicology and applied pharmacology2019

Progress in data interoperability to support computational toxicology and chemical safety evaluation.

Sean Watford, Stephen Edwards, Michelle Angrish, Richard S Judson, Katie Paul Friedman

Open access · greenAbstract readReview
In one paragraph

Review in Toxicology and applied pharmacology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
4.0field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 36 citations in OpenAlex.

  1. Weight of evidence for cross-species conservation of androgen receptor-based biological activity.Toxicological sciences : an official journal of the Society of Toxicology · 2023
    Pooled it
  2. Article
  3. Review
  4. Article
  5. Review
  6. Article
  7. Multi-Omics Strategies for Investigating the Microbiome in Toxicology Research.Toxicological sciences : an official journal of the Society of Toxicology · 2022
    Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Sean WatfordBooz Allen Hamilton, Rockville, MD 20852, USA; National Center for Computational Toxicology, Office of Research and Development, U.S. Environmental Protection Agency, Research Triangle Park, NC 27711, USA.
Stephen EdwardsResearch Triangle Institute International, Research Triangle Park, NC 27709, USA.
Michelle AngrishNational Center for Environmental Assessment, Office of Research and Development, U.S. Environmental Protection Agency, Research Triangle Park, NC 27711, USA.
Richard S JudsonNational Center for Computational Toxicology, Office of Research and Development, U.S. Environmental Protection Agency, Research Triangle Park, NC 27711, USA.
Katie Paul FriedmanNational Center for Computational Toxicology, Office of Research and Development, U.S. Environmental Protection Agency, Research Triangle Park, NC 27711, USA. Electronic address: paul-friedman.katie@epa.gov.
Environmental Protection Agency · USRTI International · US

Funding

Intramural EPA EPA999999
6 · The paper itself

Abstract

New approach methodologies (NAMs) in chemical safety evaluation are being explored to address the current public health implications of human environmental exposures to chemicals with limited or no data for assessment. For over a decade since a push toward "Toxicity Testing in the 21

Indexed as

AnimalsComputational BiologyEnvironmental ExposureEnvironmental PollutantsGenetic Predisposition to DiseaseHumansPhenotypeRisk AssessmentToxicologyEnvironmental PollutantsApplicationsBioinformaticsComputational ToxicologyDatabasesData Interoperability

Identifiers

PMID31404555
PMCPMC7705611
OpenAlexW2967389626

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.