ArticleKou qiang yi xue yan jiu = Journal of oral science research2018
Effect of Pregnancy on TMJ Nociception in Rats.
Article in Kou qiang yi xue yan jiu = Journal of oral science research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Funding
Abstract
objectiveDoes TMJ nociception, as measured by a behavioral assay, differ during pregnancy, potentially due to the effect of sex steroids?
methodsThirty - two Sprague Dawlcy rats were randomly allocated to either mid- (EH 11) or late- (EH 17) pregnancy groups. The animals within each group were further allocated to a saline or CFA treatment. At EH 11 or EH 17, the animals were injected bilaterally into TMJ with either saline (15
resultsCFA injection resulted in the animals eating longer in both the mid - pregnant and late-pregnant groups. Plasma estradiol was higher in the late - pregnant group versus the mid - pregnant group. Importantly, the CFA injected late-pregnant group ate for a shorter amount of time (i. e., shorter meal rate) than the CFA injected rats at mid - pregnancy.
conclusionThe reduced nociceptive response (shorter meal rate) in the CFA injected late - pregnant group may be due to greater estradiol versus the CFA injected mid - pregnancy rats. Thus, one potential reason why women report fewer TMJ symptoms during pregnancy is the higher level of circulating estradiol.
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