ReviewOncology letters2019
Soft tissue sarcomas of the upper extremities: Maximizing treatment opportunities and outcomes.
Review in Oncology letters, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Low-Grade Fibromyxoid Sarcoma of the Distal Upper Extremity: A Systematic Review.Hand (New York, N.Y.) · 2024Pooled it
- Free Osteocutaneous Fibular Flap for Hand Reconstruction Related to Clear Cell Sarcoma Resection: A Case Report.Cureus · 2026Article
- Reconstructive strategies using abdominal flaps for cutaneous malignancies: A case series.International journal of surgery case reports · 2025Article
- Reconstruction of the Triceps Brachii Using the Latissimus Dorsi Musculocutaneous Flap.Plastic and reconstructive surgery. Global open · 2024Article
- Descriptive analysis of incidence, demographic characteristics, and survival outcomes of soft-tissue sarcoma of the extremities in Saudi Arabia.Scientific reports · 2024Article
- Elbow sarcoma resection and triceps reconstruction with Achilles allograft: an overview, case report, and technique guide.JSES international · 2024Article
- Results of resection of forearm soft tissue sarcoma.Journal of orthopaedic surgery and research · 2023Article
- Soft Tissue Masses of the Hand: A Review of Clinical Presentation and Imaging Features.Current oncology (Toronto, Ont.) · 2023Review
- Article
- Clinical Outcomes of Soft Tissue Sarcoma around the Elbow Joint: A Retrospective Single Institution Study.Sarcoma · 2022Article
- PROMIS scores of patients undergoing neoadjuvant and adjuvant radiation therapy for surgically excised soft tissue sarcoma.Clinical and translational radiation oncology · 2021Article
- Diagnostic and Clinical Impact of 18F-FDG PET/CT in Staging and Restaging Soft-Tissue Sarcomas of the Extremities and Trunk: Mono-Institutional Retrospective Study of a Sarcoma Referral Center.Journal of clinical medicine · 2020Article
- Article
- Clinical and pathological features of upper limb nerve tumors - four years retrospective study.Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologieArticle
- Clinical and strategic outcomes of metastatic synovial sarcoma on limb.International journal of health sciencesArticle
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Soft tissue sarcomas (STS) are rare tumors; they do not even equate to 1% of all malignant tumor cases. One-fifth of all STS occur in the upper extremities, where epithelioid sarcoma, synovial sarcoma, clear cell sarcoma and malignant fibrohistiocytoma are the most frequent subtypes. Surgical resection is the cornerstone of treatment. However, accomplishment of optimal oncological and functional results of STS of the upper extremities may represent a challenge for hand surgeons, due to the complex anatomy. In several cases, preoperative therapies are needed to facilitate tumor resection and improve the oncological outcome. Oligometastatic disease may also be a challenging scenario as curative strategies can be applied. Radiotherapy and chemotherapy are commonly used for this purpose albeit with conflicting evidence. Novel drug combinations have also been approved in the metastatic setting, further improving the quality of life and survival of eligible patients. Thus, prior to any approach, every case should be individually discussed in sarcoma centers with specialized multidisciplinary tumor boards. The aim of the present review was to gather the multidisciplinary experiences of the available therapeutic strategies for STS of the upper extremities.
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Registered trials
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