Evidence map›Paper›PMID 31404168›Full record

ArticleFrontiers in immunology2019

TNF-α-Producing

Zhenzong Fa, Jintao Xu, Jiu Yi, Junjun Sang, Weihua Pan, Qun Xie, Runping Yang, Wei Fang, Wanqing Liao, Michal A Olszewski

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 26 citations in OpenAlex.

  1. A review of the current anti-New microbes and new infections · 2026
    Review
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Inbred Mouse Models inJournal of fungi (Basel, Switzerland) · 2024
    Review
  8. Global trends inFrontiers in immunology · 2024
    Article
  9. Dendritic Cells: Multifunctional Roles in Host Defenses toJournal of fungi (Basel, Switzerland) · 2023
    Review
  10. Adaptive immunology ofFrontiers in immunology · 2023
    Review
  11. The Dynamics ofCells · 2022
    Article
  12. Journal of fungi (Basel, Switzerland) · 2022
    Review
  13. Article
  14. Frontiers in immunology · 2022
    Article
  15. Article
  16. Article
  17. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Zhenzong FaDivision of Pulmonary and Critical Care Medicine, Department of Internal Medicine, University of Michigan Health System, Ann Arbor, MI, United States.
Jintao XuDivision of Pulmonary and Critical Care Medicine, Department of Internal Medicine, University of Michigan Health System, Ann Arbor, MI, United States.
Jiu YiShanghai Key Laboratory of Molecular Medical Mycology, Department of Dermatology, Changzheng Hospital, Naval Medical University, Shanghai, China.
Junjun SangShanghai Key Laboratory of Molecular Medical Mycology, Department of Dermatology, Changzheng Hospital, Naval Medical University, Shanghai, China.
Weihua PanShanghai Key Laboratory of Molecular Medical Mycology, Department of Dermatology, Changzheng Hospital, Naval Medical University, Shanghai, China.
Qun XieDepartment of Anesthesiology, The Fourth Medical Center of PLA General Hospital, Beijing, China.
Runping YangDepartment of Dermatology, The Sixth Medical Center of PLA General Hospital, Beijing, China.
Wei FangShanghai Key Laboratory of Molecular Medical Mycology, Department of Dermatology, Changzheng Hospital, Naval Medical University, Shanghai, China.
Wanqing LiaoShanghai Key Laboratory of Molecular Medical Mycology, Department of Dermatology, Changzheng Hospital, Naval Medical University, Shanghai, China.
Michal A OlszewskiDivision of Pulmonary and Critical Care Medicine, Department of Internal Medicine, University of Michigan Health System, Ann Arbor, MI, United States.
Shanghai Changzheng Hospital · CNChinese PLA General Hospital · CNMichigan Medicine · US

Funding

Modulation of Pulmonary Defenses in Pathobiology of Chronic InfectionsI01BX000656 · VA · VETERANS HEALTH ADMINISTRATION · PI OLSZEWSKI, MICHAL A · 2011 to 2025
–
BLRD VA I01 BX000656BLRD VA IK6 BX003615
6 · The paper itself

Abstract

Tumor necrosis factor alpha (TNF-α) plays a critical role in the control of cryptococcal infection, and its insufficiency promotes cryptococcal persistence. To explore the therapeutic potential of TNF-α supplementation as a booster of host anti-cryptococcal responses, we engineered a

Indexed as

Cryptococcus neoformansAnimalsCellular SenescenceCryptococcosisFemaleGenes, SyntheticLeukocytesLungLung Diseases, FungalMacrophage ActivationMacrophages, AlveolarMiceMice, Inbred BALB CModels, AnimalPlasmidsRecombinant ProteinsRecombinant ProteinsTumor Necrosis Factor-alphacryptococcosishost defenseTh1/Th2 balanceTNF-αTNF-α-producing C. neoformans

Identifiers

PMID31404168
PMCPMC6677034
OpenAlexW2957879499

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.