Evidence map›Paper›PMID 31404149›Full record

ReviewFrontiers in immunology2019

Long Non-coding RNAs: Regulators of the Activity of Myeloid-Derived Suppressor Cells.

Gabriela Leija Montoya, Javier González Ramírez, Jorge Sandoval Basilio, Idanya Serafín Higuera, Mario Isiordia Espinoza, Rogelio González González, Nicolás Serafín Higuera

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Frontiers in immunology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Review
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  3. The Role of Long Non-Coding RNA in Anxiety Disorders: A Literature Review.International journal of molecular sciences · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Gabriela Leija MontoyaFacultad de Medicina, Universidad Autónoma de Baja California, Mexicali, Mexico.
Javier González RamírezFacultad de Enfermería, Universidad Autónoma de Baja California, Mexicali, Mexico.
Jorge Sandoval BasilioLaboratorio de Biología Molecular, Universidad Hipócrates, Acapulco de Juárez, Mexico.
Idanya Serafín HigueraFacultad de Medicina, Universidad Autónoma de Baja California, Tijuana, Mexico.
Mario Isiordia EspinozaDivisión de Ciencias Biomédicas, Departamento de Clínicas, Centro Universitario de los Altos, Universidad de Guadalajara, Tepatitlán de Morelos, Guadalajara, Mexico.
Rogelio González GonzálezDepartamento de Investigación, Universidad Juárez del Estado de Durango, Durango, Mexico.
Nicolás Serafín HigueraUnidad de Ciencias de la Salud, Facultad de Odontología, Universidad Autónoma de Baja California, Mexicali, Mexico.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Myeloid-derived suppressor cells (MDSCs) are a heterogeneous cell population with potent immunosuppressive functions. They play major roles in cancer and many of the pathologic conditions associated with inflammation. Long non-coding RNAs (lncRNAs) are untranslated functional RNA molecules. The lncRNAs are involved in the control of a wide variety of cellular processes and are dysregulated in different diseases. They can participate in the modulation of immune function and activity of inflammatory cells, including MDSCs. This mini review focuses on the emerging role of lncRNAs in MDSC activity. We summarize how lncRNAs modulate the generation, recruitment, and immunosuppressive functions of MDSCs and the underlying mechanisms.

Indexed as

AnimalsCCAAT-Enhancer-Binding Protein-betaCell LineageEpigenesis, GeneticForecastingGene Expression Regulation, NeoplasticHumansImmunotherapyInflammationMiceMyeloid-Derived Suppressor CellsNeoplasmsNitric OxidePseudogenesReactive Oxygen SpeciesRNA, Long NoncodingCCAAT-Enhancer-Binding Protein-betaNitric OxideReactive Oxygen SpeciesRNA, Long NoncodingRNA, Neoplasmaccumulationcancerimmunosuppressive functioninflammationlong non-coding RNAmyeloid-derived suppressor cell

Identifiers

PMID31404149
PMCPMC6671873

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.