Evidence map›Paper›PMID 31404147›Full record

ArticleFrontiers in neurology2019

Spatial Gradient of Microstructural Changes in Normal-Appearing White Matter in Tracts Affected by White Matter Hyperintensities in Older Age.

Susana Muñoz Maniega, Rozanna Meijboom, Francesca M Chappell, Maria Del C Valdés Hernández, John M Starr, Mark E Bastin, Ian J Deary, Joanna M Wardlaw

Open access · goldAbstract read
In one paragraph

Article in Frontiers in neurology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 1 pooled it
4.1field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 1 synthesis or guideline pooled it, 32 citations in OpenAlex.

  1. Cognitive impairment in sporadic cerebral small vessel disease: A systematic review and meta-analysis.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2021
    Pooled it
  2. Article
  3. General cognitive function and the brain's structural connectome.bioRxiv : the preprint server for biology · 2026
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  17. TJournal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Susana Muñoz ManiegaNeuroimaging Sciences, Centre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, United Kingdom.
Rozanna MeijboomNeuroimaging Sciences, Centre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, United Kingdom.
Francesca M ChappellNeuroimaging Sciences, Centre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, United Kingdom.
Maria Del C Valdés HernándezNeuroimaging Sciences, Centre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, United Kingdom.
John M StarrAlzheimer Scotland Dementia Research Centre, University of Edinburgh, Edinburgh, United Kingdom.
Mark E BastinNeuroimaging Sciences, Centre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, United Kingdom.
Ian J DearyCentre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, United Kingdom.
Joanna M WardlawNeuroimaging Sciences, Centre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, United Kingdom.
University of Edinburgh · GBAlzheimer Scotland · GBUK Dementia Research Institute · GB

Funding

Medical Research Council G0701120Medical Research Council G1001245Medical Research Council MR/J006971/1Medical Research Council MR/K026992/1Medical Research Council MR/M013111/1
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

agingbraincerebral small vessel diseasediffusion MRItractographywhite matter hyperintensities

Identifiers

PMID31404147
PMCPMC6673707
OpenAlexW2962206637

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.