Evidence map›Paper›PMID 31404121›Full record

ArticleMedical archives (Sarajevo, Bosnia and Herzegovina)2019

Vitamin C May Help to Reduce the Knee's Arthritic Symptoms. Outcomes Assessment of Nutriceutical Therapy.

Umberto Ripani, Paloma Manzarbeitia-Arroba, Sandra Guijarro-Leo, Javier Urrutia-Graña, Alessandra De Masi-De Luca

Abstract read
In one paragraph

Article in Medical archives (Sarajevo, Bosnia and Herzegovina), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 28 citations in OpenAlex.

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  12. Ingredients of a Natural Oral Nutritional Supplement and Their Role in the Treatment of Osteoarthritis.Clinical medicine insights. Arthritis and musculoskeletal disorders · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Umberto RipaniPain Therapy Center, Division of Anesthesia, Analgesia and Intensive Care, Department of Emergency, Ospedali Riuniti di Ancona, Ancona, Italy.
Paloma Manzarbeitia-ArrobaDepartment of Orthopedics and Traumatology, Complejo Hospitalario Universitario de Toledo, Toledo, Spain.
Sandra Guijarro-LeoDepartment of Orthopedics and Traumatology, Complejo Hospitalario Universitario de Toledo, Toledo, Spain.
Javier Urrutia-GrañaDepartment of Orthopedics and Traumatology, Complejo Hospitalario Universitario de Toledo, Toledo, Spain.
Alessandra De Masi-De LucaRehabilitation Medical Department, Cardinale G. Panico Hospital, Tricase, Italy.
Ospedali Riuniti di Ancona · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionOsteoarthritis (OA) is a chronic joint disease characterized by degeneration of the articular cartilage, changes in the physico-chemical properties of the synovial fluid and macroscopical modifications of the joint. Patients with Classes I and II of Knee OA can be treated with pharmacologic therapy. Vitamin C is key for both preventing inflammatory arthritis and maintaining healthy joints with OA.

aimThe aim of our paper is to verify the effectiveness of the addition of vitamin c in nutriceutical drugs for the therapy of the knee arthritis in the young adult.

resultsGroup B has a lower VAS score at 6 and 12 months with p<0.05. Not statistical difference we found in KSS during all follow up. A better quality of life was founded in Group B at 12 months in group B(p<0.05) and less use of pain killers/monthly(p<0.05).

conclusionThere is no denying that vitamin C benefits everybody, whether they have arthritis or not. Therefore, it is a good idea to maintain a healthy balance of vitamin C. Without a doubt, vitamin C benefits most people with early OA.

Indexed as

AdolescentAdultAnalgesicsAntioxidantsAscorbic AcidDietary SupplementsFemaleHumansKnee JointMaleMiddle AgedMusculoskeletal PainOsteoarthritis, KneePain MeasurementYoung AdultAnalgesicsAntioxidantsAscorbic AcidAdultArthritisJointKneeOutcomesQuality LifeVitamin C

Identifiers

PMID31404121
PMCPMC6643354
OpenAlexW3004959994

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.