Evidence map›Paper›PMID 31403124›Full record

ArticleEuropean journal of obstetrics & gynecology and reproductive biology: X2019

Gestational and perinatal outcomes in recurrent miscarriages couples treated with lymphocyte immunotherapy.

Manoel Sarno, Marcelo Borges Cavalcante, Marla Niag, Kleber Pimentel, Ivana Luz, Bianca Figueiredo, Tatiana Michelon, Jorge Neumann, Simone Lima, Isabela Nelly Machado and 2 more

Open access · goldAbstract read
In one paragraph

Article in European journal of obstetrics & gynecology and reproductive biology: X, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 22 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 1 country.

Manoel SarnoDepartment of Obstetrics and Gynecology, Federal University of Bahia (UFBA), Salvador, BA, Brazil.
Marcelo Borges CavalcanteDepartment of Obstetrics and Gynecology, Fortaleza University (UNIFOR), Fortaleza, CE, Brazil.
Marla NiagDepartment of Obstetrics and Gynecology, Federal University of Bahia (UFBA), Salvador, BA, Brazil.
Kleber PimentelDepartment of Obstetrics and Gynecology, Federal University of Bahia (UFBA), Salvador, BA, Brazil.
Ivana LuzAloimune Reproductive Immunology Centre, Salvador, BA, Brazil.
Bianca FigueiredoReproductive Immunology Centre, Rio de Janeiro, RJ, Brazil.
Tatiana MichelonReproductive Immunology Centre, Porto Alegre, RS, Brazil.
Jorge NeumannReproductive Immunology Centre, Porto Alegre, RS, Brazil.
Simone LimaAllovita Reproductive Immunology Centre, Campinas, SP, Brazil.
Isabela Nelly MachadoAllovita Reproductive Immunology Centre, Campinas, SP, Brazil.
Edward Araujo JúniorDepartment of Obstetrics, Paulista School of Medicine-Federal University of São Paulo (EPM-UNIFESP), São Paulo, SP, Brazil.
Ricardo BariniDepartment of Obstetrics and Gynecology, State University of Campinas (UNICAMP), Campinas, SP, Brazil.
Universidade Federal da Bahia · BRUniversidade de Fortaleza · BRUniversidade Estadual de Campinas (UNICAMP) · BRUniversidade Federal de São Paulo · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThis study aims to elucidate which types of recurrent miscarriage (RM) patients experienced a livebirth after paternal lymphocyte immunotherapy (LIT) and to evaluate the perinatal outcome. STUDY

designRetrospective analysis of a multicenter, observational study which enrolled 1096 couples with a history of two or more spontaneous miscarriages without any intercalated delivery. We conducted an intention-to-treat analysis of couples with RM treated with or without LIT regarding to gestational and perinatal outcomes. We compared groups by using the Student's

resultsThe success of gestation was significantly higher in the LIT group (60.1% vs. 33.1%;

conclusionsCareful laboratory test phenotyping of RM patients may identify subgroups most likely to benefit and exclude those with little likelihood of benefit, and LIT during a pregnancy may significantly improve success rates.

Indexed as

GestationLymphocyte immunotherapyPerinatal outcomesRecurrent miscarriage

Identifiers

PMID31403124
PMCPMC6687386
OpenAlexW2944786495

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.