ReviewFrontiers in chemistry2019
Nitric Oxide (NO)-Releasing Macromolecules: Rational Design and Biomedical Applications.
Review in Frontiers in chemistry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed.
- Network Silsesquioxane-Based Organogel/Silicone Composites for the Long-Lasting Delivery of Nitric Oxide.Molecules (Basel, Switzerland) · 2026Article
- Chitosan-based hydrogels for nitric oxide-mediated myocardial repair: advances and prospects.Journal of biological engineering · 2026Review
- Development of a nitric oxide-releasing cephalexin-based hybrid compound for enhanced antimicrobial efficacy and biofilm disruption.RSC medicinal chemistry · 2025Article
- Nitric Oxide Therapeutics: New Hopes for More Effective Tuberculosis Treatment Combine with Targeted and Controlled Nanotechnology.International journal of nanomedicine · 2025Review
- Naphthalimide-based light-induced nitric oxide-releasing nanoscale vesicles with visual detection and cytotoxicity studies.iScience · 2024Article
- Hemin as a Molecular Probe for Nitric Oxide Detection in Physiological Solutions: Experimental and Theoretical Assessment.Analytical chemistry · 2024Article
- Near-infrared light-responsive Nitric oxide microcarrier for multimodal tumor therapy.Smart medicine · 2023Article
- Nucleotide Messenger Signaling of Staphylococci in Responding to Nitric Oxide - Releasing Biomaterials.ACS biomaterials science & engineering · 2023Article
- Nitric Oxide (NO) as a Reagent for Topochemical Framework Transformation and Controlled NO Release in Covalent Organic Frameworks.Journal of the American Chemical Society · 2023Article
- Synthesis and Characterization of Nitric Oxide-Releasing Ampicillin as a Potential Strategy for Combatting Bacterial Biofilm Formation.ACS applied materials & interfaces · 2023Article
- Intelligent polymeric hydrogen sulfide delivery systems for therapeutic applications.Bioactive materials · 2023Review
- Nitric oxide boosters as defensive agents against COVID-19 infection: an opinion.Journal of biomolecular structure & dynamics · 2022Article
- Improved Polymer Hemocompatibility for Blood-Contacting Applications viaACS applied materials & interfaces · 2022Article
- Surface Texturing and Combinatorial Approaches to Improve Biocompatibility of Implanted Biomaterials.Frontiers in physics · 2022Article
- Stimuli Responsive Nitric Oxide-Based Nanomedicine for Synergistic Therapy.Pharmaceutics · 2021Review
- Nitric oxide releasing halloysite nanotubes for biomedical applications.Journal of colloid and interface science · 2021Article
- Nitric oxide and viral infection: Recent developments in antiviral therapies and platforms.Applied materials today · 2021Review
- 3D bioprinting of integral ADSCs-NO hydrogel scaffolds to promote severe burn wound healing.Regenerative biomaterials · 2021Article
- Engineering Metal-Organic Frameworks (MOFs) for Controlled Delivery of Physiological Gaseous Transmitters.Nanomaterials (Basel, Switzerland) · 2020Review
- Mode of nitric oxide delivery affects antibacterial action.ACS biomaterials science & engineering · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Nitric oxide (NO) has been recognized as a ubiquitous gaseous transmitter and the therapeutic potential has nowadays received increasing interest. However, NO cannot be easily directly administered due to its high reactivity in air and high concentration-dependent physiological roles. As such, a plethora of NO donors have been developed that can reversibly store and release NO under specific conditions. To enhance the stability and modulate the NO release profiles, small molecule-based NO donors were covalently linked to polymeric scaffolds, rendering them with multifunctional integration, prolonged release durations, and optimized therapeutic outcomes. In this minireview, we highlight the recent achievements of NO-releasing macromolecules in terms of chemical design and biomedical applications. We hope that more efforts could be devoted to this emerging yet promising field.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.