ArticleTranslational vision science & technology2019
Retinal Vascular Oxygen Saturation and Its Variation With Refractive Error and Axial Length.
Article in Translational vision science & technology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
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Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.
- Refractive Error and Eye Health: An Umbrella Review of Meta-Analyses.Frontiers in medicine · 2021Pooled it
- Highland environment and genetic background are associated with myopia risk in Tibetans and Hans.Eye (London, England) · 2026Article
- Changes in retinal oxygen saturation before and after femtosecond LASIK in adult myopic individuals with anisometropia.Scientific reports · 2026Observational
- Characteristics of Retinal Oxygen Kinetics and Blood Flow in Myopia of Different Degrees.Investigative ophthalmology & visual science · 2025Article
- Retinal oximetry: new insights into ocular and systemic diseases.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2025Review
- Changes in Retinal Oxygen Saturation 1 Month After Femtosecond LASIK Treatment in Chinese Adults with Myopia.Ophthalmology and therapy · 2025Article
- Relationship Between Axial Length and Retinal Oxygen Dynamics in Adults With Myopia.Translational vision science & technology · 2025Observational
- Effect of Refractive Status on Peripapillary Retinal Nerve Fiber Layer Thickness and Vascular Density: A Prospective Optical Coherence Tomography Angiography-Based Study.Medical journal of the Islamic Republic of Iran · 2025Article
- Hemoglobin oxygen saturation in myopic eyes: a scanning laser ophthalmoscope study.International journal of ophthalmology · 2025Article
- Changes in retinal vessel oxygen saturation using automated retinal oximetry in patients with significant carotid stenosis.Frontiers in neurology · 2025Article
- Retinal Vascular Oxygen Saturation in a Sample of Chinese Myopic Adults.Investigative ophthalmology & visual science · 2023Observational
- Retinal Vascular Oxygen Saturation in Adults With Anisometropia.Translational vision science & technology · 2023Observational
- Evidence of vascular involvement in myopia: a review.Frontiers in medicine · 2023Review
- Functions of retinal astrocytes and Müller cells in mammalian myopia.BMC ophthalmology · 2022Article
- Hemodynamic and morphological changes of the central retinal artery in myopic eyes.Scientific reports · 2022Article
- Retinal Oxygen Delivery and Extraction in Ophthalmologically Healthy Subjects With Different Blood Pressure Status.Translational vision science & technology · 2022Article
- Retinal Vessel Oxygen Saturation Measurement Protocols and Their Agreement.Translational vision science & technology · 2020Article
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo evaluate the relationships between refractive error, axial length (AL), and retinal vascular oxygen saturation in an adult population.
methodsThis was a hospital-based, prospective observational study. The left eyes of phakic adult subjects without media opacity were analyzed. Subjective undilated manifest refraction was performed, and refractive errors were defined as myopia (spherical equivalent [SE], <-1 D), emmetropia (SE between -1 D and +1 D) and hyperopia (SE >+1 D). Retinal oximetry was performed using the Oxymap system (Oxymap Inc., Reykjavik, Iceland). Multivariate linear regression models were constructed to assess the relationship between retinal vascular oxygen saturation, SE, and AL obtained with optical biometry, with adjustments for age, sex, race, blood pressure, hyperlipidemia, and diabetes mellitus.
resultsThere were 85 subjects, with mean age of 66.1 ± 11.3 years. The majority were female (60%) and Chinese (84%). A total of 60% were myopic, 28% emmetropic, and 12% hyperopic. Mean SE was -5.29 ± 6.51 D and mean AL was 25.30 ± 2.99 mm. In multivariate analyses, more myopic SE and longer AL were associated with lower retinal arteriolar oxygen saturation (regression coefficient B = 0.61 [95% confidence interval, 0.28, 0.95],
conclusionsEyes with more myopic SE and longer AL have lower retinal arteriolar oxygen saturation. TRANSLATIONAL RELEVANCE: This study provides direct evidence of a link between retinal oxygenation and hypoxia and myopia by using a novel device that quantifies retinal vascular oxygenation in vivo.
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