Evidence map›Paper›PMID 31402954›Full record

ArticleOncology letters2019

miR-296-3p targets APEX1 to suppress cell migration and invasion of non-small-cell lung cancer.

Lifeng Wang, Ruilin Chen, Yongqing Zhang

Open access · diamondAbstract read
In one paragraph

Article in Oncology letters, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
1.1field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 27 citations in OpenAlex.

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  16. HDAC3 deteriorates colorectal cancer progression via microRNA-296-3p/TGIF1/TGFβ axis.Journal of experimental & clinical cancer research : CR · 2020
    Article
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  19. Non-Coding RNAs in Lung Tumor Initiation and Progression.International journal of molecular sciences · 2020
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Lifeng WangDepartment of Respiration, Xi'an High-tech Hospital, Xi'an, Shaanxi 710075, P.R. China.
Ruilin ChenDepartment of Respiration, Shaanxi Provincial People's Hospital, Xi'an, Shaanxi 710068, P.R. China.
Yongqing ZhangDepartment of Respiration, Shaanxi Provincial People's Hospital, Xi'an, Shaanxi 710068, P.R. China.
Shanxi Medical University · CNXi'an High Tech University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Non-small-cell lung cancer (NSCLC) is the most common cause of cancer-associated mortality worldwide. MicroRNAs (miRs) are a class of small non-coding RNAs that are commonly dysregulated in human cancer. The aim of the current study was to evaluate the effect of miR-296-3p on the cell migration and invasion of NSCLC. Pairs of tumor tissues and para-cancerous tissues (n=50) were collected from patients with NSCLC, and the expression of miR-296-3p was analyzed by reverse transcription-quantitative polymerase chain reaction (RT-qPCR). Additionally, tumor cell viability, migration and invasion were examined

Indexed as

apurinic/apyrimidinic endodeoxyribonuclease 1invasionmicroRNA-296-3pmigrationnon-small-cell lung cancer

Identifiers

PMID31402954
PMCPMC6676713
OpenAlexW2954606751

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.