Evidence map›Paper›PMID 31402918›Full record

ArticleFrontiers in immunology2019

A Novel, Five-Marker Alternative to CD16-CD14 Gating to Identify the Three Human Monocyte Subsets.

Siew-Min Ong, Karen Teng, Evan Newell, Hao Chen, Jinmiao Chen, Thomas Loy, Tsin-Wen Yeo, Katja Fink, Siew-Cheng Wong

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 71 papers.

0numbers the graph read from it
0cells of the map it votes in
71citing papers in PubMed
5.6field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

71 citing papers in PubMed, 121 citations in OpenAlex.

  1. Trial
  2. Article
  3. Induction of dysfunctional CD14Frontiers in immunology · 2026
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  11. DOGMA-seq and multimodal, single-cell analysis in acute myeloid leukemia.International review of cell and molecular biology · 2025
    Review
  12. Article
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  14. Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Article
  20. Article

11 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Siew-Min OngSingapore Immunology Network (SIgN), ASTAR Research Entities, Singapore, Singapore.
Karen TengSingapore Immunology Network (SIgN), ASTAR Research Entities, Singapore, Singapore.
Evan NewellSingapore Immunology Network (SIgN), ASTAR Research Entities, Singapore, Singapore.
Hao ChenSingapore Immunology Network (SIgN), ASTAR Research Entities, Singapore, Singapore.
Jinmiao ChenSingapore Immunology Network (SIgN), ASTAR Research Entities, Singapore, Singapore.
Thomas LoySingapore Immunology Network (SIgN), ASTAR Research Entities, Singapore, Singapore.
Tsin-Wen YeoNational Centre for Infectious Diseases, Singapore, Singapore.
Katja FinkSingapore Immunology Network (SIgN), ASTAR Research Entities, Singapore, Singapore.
Siew-Cheng WongSingapore Immunology Network (SIgN), ASTAR Research Entities, Singapore, Singapore.
Singapore Immunology Network · SGNanyang Technological University · SGNational Centre for Infectious Diseases · SG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Human primary monocytes are heterogeneous in terms of phenotype and function, but are sub-divided only based on CD16 and CD14 expression. CD16 expression distinguishes a subset of monocytes with highly pro-inflammatory properties from non-CD16 expressing "classical" monocytes. CD14 expression further subdivides the CD16

Indexed as

BiomarkersCell PlasticityHumansImmunophenotypingLeukocytes, MononuclearLipopolysaccharide ReceptorsMonocytesReceptors, IgGBiomarkersLipopolysaccharide ReceptorsReceptors, IgGCD14CD16cytometrydenguemonocyte subsets

Identifiers

PMID31402918
PMCPMC6676221
OpenAlexW2957445014

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.