Evidence map›Paper›PMID 31402860›Full record

ArticleFrontiers in aging neuroscience2019

Endogenous HCN Channels Modulate the Firing Activity of Globus Pallidus Neurons in Parkinsonian Animals.

Xiao-Meng Hao, Rong Xu, An-Qi Chen, Feng-Jiao Sun, Ying Wang, Hong-Xia Liu, Hua Chen, Yan Xue, Lei Chen

Abstract read
In one paragraph

Article in Frontiers in aging neuroscience, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Characterization of Effectiveness in ConcertedInternational journal of molecular sciences · 2020
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Xiao-Meng HaoDepartment of Physiology, Qingdao University, Qingdao, China.
Rong XuDepartment of Physiology, Qingdao University, Qingdao, China.
An-Qi ChenDepartment of Physiology, Qingdao University, Qingdao, China.
Feng-Jiao SunDepartment of Physiology, Qingdao University, Qingdao, China.
Ying WangDepartment of Physiology, Qingdao University, Qingdao, China.
Hong-Xia LiuDepartment of Physiology, Qingdao University, Qingdao, China.
Hua ChenDepartment of Pathology, Qingdao Municipal Hospital, Qingdao, China.
Yan XueDepartment of Physiology, Qingdao University, Qingdao, China.
Lei ChenDepartment of Physiology, Qingdao University, Qingdao, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The globus pallidus occupies a critical position in the indirect pathway of the basal ganglia motor control system. Hyperpolarization-activated cyclic-nucleotide gated (HCN) channels play an important role in the modulation of neuronal excitability.

Indexed as

basal gangliaglobus pallidushyperpolarization-activated cyclic nucleotide-gated channelParkinson’s diseasesingle unit recording

Identifiers

PMID31402860
PMCPMC6670024

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.