ArticleJournal of clinical laboratory analysis2019
Neutrophil-to-lymphocyte ratio and platelet-to-lymphocyte ratio are associated with disease activity in polymyalgia rheumatica.
Article in Journal of clinical laboratory analysis, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
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Who cites it
27 citing papers in PubMed, 44 citations in OpenAlex.
- Inflammatory blood count ratios discriminate disease activity and remain persistently elevated during glucocorticoid-free remission in ANCA-associated vasculitis.Clinical and experimental medicine · 2026Article
- Age and neutrophil counts at the time of diagnosis of polymyalgia rheumatica: are they useful or confounding factors in the geriatrician's clinical practice?European geriatric medicine · 2026Article
- Time to remission and steroid doses in older and younger patients with polymyalgia rheumatica.European geriatric medicine · 2026Article
- Utility of CBC-derived ratios in the diagnosis and prediction of active tuberculosis in people with rheumatic diseases.BMC infectious diseases · 2026Article
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- Diagnostic and prognostic utility of complete blood count-derived ratios in giant cell arteritis: a retrospective fast-track clinic cohort study.Rheumatology international · 2025Article
- Correlation and Risk Assessment of Inflammation-Based Parameters on Cardiovascular Parameters and Clinical Events in Giant Cell Arteritis: A Retrospective Study.International journal of molecular sciences · 2025Article
- Current Insights and Future Perspectives for the Use of Serological Biomarkers in Polymyalgia Rheumatica.Journal of inflammation research · 2025Review
- Choroidal thickness as a biomarker of systemic inflammation in patients with polymyalgia rheumatica.Frontiers in medicine · 2025Article
- NLR (neutrophil to lymphocyte ratio), PLR (platelet to lymphocyte ratio), and SII (systemic immune-inflammation index) reflect disease activity and renal remission in patients with lupus nephritis.Frontiers in immunology · 2025Article
- Correlation between CBC-derived inflammatory indicators and all-cause mortality with rheumatoid arthritis: a population-based study.Frontiers in medicine · 2025Article
- Correlation study of multiple inflammatory indices and vertebral compression fracture: A cross-sectional study.Journal of clinical & translational endocrinology · 2024Article
- Potential biomarkers in Behçet's disease: monocyte, neutrophil, platelet, and C-reactive protein to albumin ratios.Reumatologia · 2024Article
- The relationship of neutrophil-to-lymphocyte ratio with health-related quality of life, depression, and disease activity in SLE: a cross-sectional study.Rheumatology international · 2023Article
- Immune complex-mediated neutrophil activation in patients with polymyalgia rheumatica.Rheumatology (Oxford, England) · 2023Article
- [Methods for assessment of disease activity of polymyalgia rheumatica].Zeitschrift fur Rheumatologie · 2023Review
- Elevated Cardiovascular Disease Risk in Patients with Restless Legs Syndrome.Alpha psychiatry · 2023Article
- Prevalence and risk factors of herpes zoster infection in patients with rheumatic diseases not receiving biologic or targeted therapies.Clinical rheumatology · 2023Article
- Relapsing polychondritis: focus on cardiac involvement.Frontiers in immunology · 2023Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
backgroundThe neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), and monocyte-to-lymphocyte ratio (MLR) are indicators of systemic inflammation and are useful as markers in systemic rheumatic diseases. In this study, we compared the NLR, PLR, and MLR among patients with polymyalgia rheumatica (PMR) and rheumatoid arthritis (RA), and explored possible associations with clinical features, disease activity, and prognosis in patients with PMR.
methodsThe study enrolled 94 patients with PMR and 242 patients with RA who were initially diagnosed at the rheumatology clinic of a university-based tertiary hospital. Symptoms, physical examination, and medical histories were collected with the results of laboratory tests.
resultsNeutrophil-to-lymphocyte ratio (4.5 ± 3.3 vs 2.8 ± 1.8), PLR (222.7 ± 115.5 vs 159.7 ± 78.1), and MLR (0.4 ± 0.3 vs 0.3 ± 0.2) were higher in patients with PMR compared with patients with RA (all P < .001). NLR, PLR, and MLR were correlated with specific laboratory values, including CRP and albumin, in patients with PMR. After disease activity resolved, NLR (2.95 ± 2.32, P < .001), PLR (137.5 ± 82.3, P < .001), and MLR (0.26 ± 0.16, P < .001) decreased significantly. By comparing patients according to the disease course, swollen joint counts were higher in the chronic course group compared with the remission group (P = .03), while the NLR, PLR, and MLR were similar.
conclusionsNeutrophil-to-lymphocyte ratio, platelet-to-lymphocyte ratio, and monocyte-to-lymphocyte ratio levels were associated with disease activity and specific clinical features, although they could not predict prognosis in patients with PMR.
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