Evidence map›Paper›PMID 31402369›Full record

ReviewChemical Society reviews2019

Bioapplications of DNA nanotechnology at the solid-liquid interface.

Wenjing Wang, Sha Yu, Shan Huang, Sai Bi, Heyou Han, Jian-Rong Zhang, Yi Lu, Jun-Jie Zhu

Open access · greenAbstract readReview
In one paragraph

Review in Chemical Society reviews, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
4.8field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 98 citations in OpenAlex.

  1. Review
  2. Review
  3. High-Entropy Materials for Prospective Biomedical Applications: Challenges and Opportunities.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024
    Review
  4. Nucleic acid nanostructures forApplied physics reviews · 2023
    Review
  5. Article
  6. Review
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Review
  16. Article
  17. Article
  18. Life at the interface: Engineering bio-nanomaterials through interfacial molecular self-assembly.Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Wenjing WangState Key Laboratory of Analytical Chemistry for Life Science, School of Chemistry & Chemical Engineering, Nanjing University, Nanjing 210023, China. jjzhu@nju.edu.cn jrzhang@nju.edu.cn.
Sha Yu
Shan Huang
Sai Bi
Heyou Han
Jian-Rong Zhang
Yi Lu
Jun-Jie Zhu
State Key Laboratory of Analytical Chemistry for Life ScienceHuazhong Agricultural University · CNQingdao University · CNUniversity of Illinois Urbana-Champaign · US

Funding

Selection and Sensing Applications of DNAzymes Selective for Paramagnetic Metal IonsR01GM124316 · NIGMS · UNIVERSITY OF TEXAS AT AUSTIN · PI LU, YI · 2017 to 2020
$1.4M
Novel DNAzyme sensors for lithium and sodium to understand cellular and molecular mechanisms of lithium treatment of bipolar disorderR21MH110975 · NIMH · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI LU, YI · 2016 to 2017
$401k
NIGMS NIH HHS R01 GM124316NIMH NIH HHS R21 MH110975
6 · The paper itself

Abstract

DNA nanotechnology engineered at the solid-liquid interface has advanced our fundamental understanding of DNA hybridization kinetics and facilitated the design of improved biosensing, bioimaging and therapeutic platforms. Three research branches of DNA nanotechnology exist: (i) structural DNA nanotechnology for the construction of various nanoscale patterns; (ii) dynamic DNA nanotechnology for the operation of nanodevices; and (iii) functional DNA nanotechnology for the exploration of new DNA functions. Although the initial stages of DNA nanotechnology research began in aqueous solution, current research efforts have shifted to solid-liquid interfaces. Based on shape and component features, these interfaces can be classified as flat interfaces, nanoparticle interfaces, and soft interfaces of DNA origami and cell membranes. This review briefly discusses the development of DNA nanotechnology. We then highlight the important roles of structural DNA nanotechnology in tailoring the properties of flat interfaces and modifications of nanoparticle interfaces, and extensively review their successful bioapplications. In addition, engineering advances in DNA nanodevices at interfaces for improved biosensing both in vitro and in vivo are presented. The use of DNA nanotechnology as a tool to engineer cell membranes to reveal protein levels and cell behavior is also discussed. Finally, we present challenges and an outlook for this emerging field.

Indexed as

NanotechnologyDNAKineticsNucleic Acid ConformationNucleic Acid HybridizationDNA

Identifiers

PMID31402369
PMCPMC6746594
OpenAlexW2967956164

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.