Evidence map›Paper›PMID 31401796›Full record

ArticleNeurology and therapy2019

Modeling the Choice Between Risperidone Long-Acting Injectable and Generic Risperidone from the Perspective of a Japanese Hospital.

Yusuke Nakamura, Isao Shibata, Jörg Mahlich

Abstract read
In one paragraph

Article in Neurology and therapy, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Yusuke NakamuraJanssen K.K., Tokyo, Japan.
Isao ShibataKawaguchi Clinic, Saitama, Japan.
Jörg MahlichHealth Economics and Outcomes Research, Janssen-Cilag, Neuss, Germany. joerg.mahlich@gmail.com.ORCID http://orcid.org/0000-0003-1110-2793

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe Japanese government's current policy is to encourage hospitals to discharge hospital patients with schizophrenia earlier and provide them with community care. This study aims to analyze clinical and economic outcomes of different discharge strategies in psychiatric hospitals in Japan.

methodsA simulation was conducted to compare patient relapse and hospital revenues for different discharge plans. We constructed a decision tree where each tree consists of a different Markov chain that models hospital revenue for four different discharge plans: discharge of the patient after 1, 2, or 3 months, or 4 months or more. The simulation also included variations in the medical treatment regimen in an outpatient setting as part of the discharge strategy. In particular, we looked at the choice between risperidone long-acting injectable (RLAI) and generic risperidone (RIS GE).

resultsThe use of RLAI in an outpatient setting reduced the number of rehospitalizations compared to generic risperidone use under all discharge plans. Different discharge plans were associated with differences in economic outcomes as well. One of the key revenue drivers for the hospital was the continuation of treatment in the outpatient setting after discharge.

conclusionThe use of RLAI in an outpatient setting could help to prevent rehospitalization, thereby contributing to better community care.

fundingThe Rapid Service Fee was funded by Janssen KK.

Indexed as

EconomicsJapanRelapseRevenue driverRisperidone long-acting injectableSchizophrenia

Identifiers

PMID31401796
PMCPMC6858920

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